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Compares two antibiotics for flare-ups of chronic lung disease

Tests doxycycline against levofloxacin in adults with COPD during a flare-up.

Plain-language title generated from the registry record
Registry title: A Study Comparing Doxycycline and Levofloxacin for Treating COPD Exacerbations

Key facts

Where
Lahore, PakistanSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 40 and 70 years old?

Source: NCT06915688, who can take part

Where in Pakistan

  • General hospitalLahore, PakistanNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Amina Aslam
Trial code
NCT06915688
Record updated
8 April 2025
Original description
This study will include patients with chronic obstructive pulmonary disease (COPD) who present with an acute exacerbation. Participants will be randomly assigned to receive either doxycycline or levofloxacin for 5 days. The aim is to compare how effective each antibiotic is in improving symptoms after 2 days of treatment.Read full original descriptionShow less

Comparison of Clinical Cure Rate of Doxycycline and Levofloxacin in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease

This study will include patients with chronic obstructive pulmonary disease (COPD) who present with an acute exacerbation. Participants will be randomly assigned to receive either doxycycline or levofloxacin for 5 days. The aim is to compare how effective each antibiotic is in improving symptoms after 2 days of treatment.

Inclusion: diagnosed cases of COPD Exacerbation of COPD Able to provide Written consent No anti biotic taken with in past 4 weeks.

Exclusion: hypersensitivity to any drugs Pneumonia evidence on xray/ hrct chest Any other pulmonary condition e.g asthma Pregnancy/breast feeding Taking treatment for other active infections.

ClinicalTrials.gov NCT06915688