Tests a breathing exercise app in adults with high blood pressure
Tests guided breathing exercises through an app in adults with prehypertension or hypertension.
Plain-language title generated from the registry record
Registry title: Breathing Exercises of CardioBreath Application on Autonomic and Vascular Function in Hypertension
Key facts
- Where
- Porto Alegre, BrazilSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT06917729, who can take part
Where in Brazil
- Instituto de Cardiologia do Rio Grande do SulPorto Alegre, BrazilNo longer taking part
- Instituto de Cardiologia do RioGrande do SulPorto Alegre, BrazilNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Instituto de Cardiologia do Rio Grande do Sul
- Trial code
- NCT06917729
- Record updated
- 8 April 2025
- Original description
Hypertension is one of the greatest public health challenges, affecting more than one billion people worldwide and representing a significant financial and public health burden. It is responsible for a high number of cardiovascular events, such as heart attacks and strokes. Although pharmacological treatment is effective, non-pharmacological interventions are essential for the sustainable management of blood pressure, especially in its early stages. Respiratory exercises have shown potential in reducing blood pressure and improving cardiac vagal modulation, promoting cardiovascular health benefits.Read full original descriptionShow less
Responses on Arterial Stiffness and Cardiac Vagal Modulation to Breathing Exercises Through the Use of CardioBreath Application in Hypertension and Pre Hypertension; a Randomized Clinical Trial
Hypertension is one of the greatest public health challenges, affecting more than one billion people worldwide and representing a significant financial and public health burden. It is responsible for a high number of cardiovascular events, such as heart attacks and strokes. Although pharmacological treatment is effective, non-pharmacological interventions are essential for the sustainable management of blood pressure, especially in its early stages. Respiratory exercises have shown potential in reducing blood pressure and improving cardiac vagal modulation, promoting cardiovascular health benefits.
This study aims to evaluate the effectiveness of guided respiratory exercises using the CardioBreath app in improving vagal modulation and reducing arterial stiffness in adults with prehypertension or hypertension over six weeks. This is a randomized clinical trial involving adults with prehypertension or hypertension, divided into intervention and control groups. The intervention group will use CardioBreath to perform daily breathing exercises, with weekly remote monitoring. Assessments will include heart rate variability parameters, baroreflex sensitivity, pulse wave velocity, and quality of life.
It is expected that the use of the app will significantly improve vagal modulation and arterial stiffness, demonstrating the potential of this intervention for the non-pharmacological management of hypertension. The use of CardioBreath may offer an accessible and effective alternative for blood pressure control, with the potential to be integrated into public health programs focused on low-cost, highly accessible interventions for the prevention and management of hypertension.
Inclusion: BP>130mmHg X 80mmHg or previous medical diagnosis of pre- hypertension or hypertension.
Exclusion: drugs that depress the central nervous system; clinical conditions that prevent participation after evaluation by the team; use of beta-blockers; individuals without a cell phone or tablet (which would make the proposed study unfeasible.