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Swallowed camera capsule checks bowel for cancer after gut-bacteria blood infection

Uses a swallowed camera capsule to look for bowel cancer in adults with blood infection.

Plain-language title generated from the registry record
Registry title: Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria

Key facts

Where
Odense, DenmarkSee the site

Where in Denmark

  • Odense University HospitalOdense, DenmarkTaking people

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Trial details

Who runs it
Odense University Hospital
Trial code
NCT06919068
Record updated
18 November 2025
Original description
The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria. The main question it aims to answer is:Read full original descriptionShow less

Colonic Capsule Endoscopy for Screening of Neoplasms in Patients With Anaerobic Bacteremia

The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria. The main question it aims to answer is:

• How prevalent is cancer and precancerous tumors in the large intestines and rectum in patients with anaerobic bacteremia? Participants will be offered an examination using colon capsule endoscopy 4-8 weeks after discharge.

Inclusion: Older than 18 years; Blood culture with growth of one or more of the following bacterial genera Bacteroides, Clostridium, Filifactor, Fusobacterium, Gemella, Granulicatella, Parvimonas, Peptostreptococcus, Prevotella, Solobacterium, Peptoniphilus, Ruminococcus, Finegoldia and Streptococcus; Able to provide oral and written informed consent; Able to read and speak Danish.

Exclusion: Prior colorectal cancer diagnosis; Previous treatment of inflammatory bowel disease; Previous major surgery of the gastrointesinal tract (e.g. gastric bypass); History of stenosis of the gastrointestinal tract; Allergies to the bowel preparation regimen; Severe kidney disease; Focus of infection in skin and soft tissue or outside the truncus (e.g. decubitus, diabetic foot ulcer); Colostomy; Pacemaker/ICD; Pregnancy or breastfeeding; Tumor in the colon or rectum at diagnostic imaging; Transfer to other hospital outside the region.

ClinicalTrials.gov NCT06919068