Studying False-Positive HLA Antibody Test Results in People With Systemic Lupus Erythematosus
Looks at false-positive HLA antibody tests in adults with systemic lupus erythematosus.
Plain-language title generated from the registry record
Registry title: HLA Antibodies in Systemic Lupus Erythematosus
Key facts
- Where
- Amiens, FranceSee the site
Where in France
- CHRU AmiensAmiens, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Centre Hospitalier Universitaire, Amiens
- Trial code
- NCT06921239
- Record updated
- 16 January 2026
- Original description
Patients suffering from autoimmune diseases show false-positive results when anti-HLA antibodies are identified. This false positivity makes it difficult to obtain an organ transplant based on immunological compatibility (absence of anti-HLA antibodies directed against graft antigens). The objectives of this project are to study the prevalence of these false positivities in a population of lupus patients, and to evaluate biological tests that can negate these false positivities.Read full original descriptionShow less
HLA Antibodies in Systemic Lupus Erythematosus
Patients suffering from autoimmune diseases show false-positive results when anti-HLA antibodies are identified. This false positivity makes it difficult to obtain an organ transplant based on immunological compatibility (absence of anti-HLA antibodies directed against graft antigens). The objectives of this project are to study the prevalence of these false positivities in a population of lupus patients, and to evaluate biological tests that can negate these false positivities.
Inclusion: Patients Adults; Followed in the internal medicine department of Amiens University Hospital - With systemic lupus erythematosus; Without HLA immunization risk factors (no history of pregnancy, transfusions or transplants); With sera stored in the biobank.
Exclusion: minor Patients; Opposing the re-use of their personal data for research purposes.