Comparing two image-guided lung biopsy methods for suspected lung growths
Compares PET/CT-guided and CT-guided needle biopsies in adults with suspected lung tumors.
Plain-language title generated from the registry record
Registry title: PET/CT GUIDED BIOPSY VERSUS CT GUIDED BIOPSY IN EVALUATION OF SUSPECTED LUNG NEOPLASMS
Key facts
- Where
- Bhubaneswar, IndiaSee the site
Where in India
- All India Institute of Medical Sciences, BhubaneswarBhubaneswar, IndiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- All India Institute of Medical Sciences, Bhubaneswar
- Trial code
- NCT06923098
- Record updated
- 11 April 2025
- Original description
Percutaneous CT guided biopsy is a well-established, standard sampling technique for suspected neoplastic lesions located in peripheral region in lung parenchyma. Inconclusive results on CT guided biopsy is substantially higher in large lung lesions which are prone to cause peripheral pneumonia, atelectasis and even regional necrosis, which are hard to be distinguished from tumor on CT images.Read full original descriptionShow less
PET/CT GUIDED BIOPSY VERSUS CT GUIDED BIOPSY IN EVALUATION OF SUSPECTED LUNG NEOPLASMS
Percutaneous CT guided biopsy is a well-established, standard sampling technique for suspected neoplastic lesions located in peripheral region in lung parenchyma. Inconclusive results on CT guided biopsy is substantially higher in large lung lesions which are prone to cause peripheral pneumonia, atelectasis and even regional necrosis, which are hard to be distinguished from tumor on CT images.
Functional imaging guided biopsy like PET/CT guided biopsy identifies areas of highest concentration of neoplastic cells and provides accurate results. Only a few studies have been done regarding PET/CT guided biopsy and studies omparing PET/CT guided and CT guided percutaneous transthoracic lung biopsy are very few and this study would be a randomized trial comparing these diagnostic modalities in terms of diagnostic yield, diagnostic accuracy of sample and complications.
Inclusion: Age above 18 years; INR \< 1.2 and platelet counts \> 80,000/mm3; CT thorax with lung lesion more than 10 mm; Accessible lesions for CT-guided biopsy.
Exclusion: Participants with pre-existing bleeding diathesis like hemophilia, coagulopathy defined by -INR ≥1.2 and Platelet counts ≤ 80,000/mm3; Serum creatinine level more than 2mg/dl; Participants who refuse to provide consent; Signs of hypoperfusion like hypotension, cyanosis etc; Presence of hypoxemia with SpO2 < 94 %- measured in a pulse oximeter); Pregnant/Lactating female subjects; Non-cooperative subjects; Lesions that are inaccessible (decision made on pre-biopsy planning).