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Study of itching triggered by light touch in atopic dermatitis

Studies how often light touch causes itching in adults with atopic dermatitis.

Plain-language title generated from the registry record
Registry title: Study of Alloknesia in Atopic Dermatitis

Key facts

Where
Angers, Brest, La Roche-sur-Yon, Lorient, Nantes, Rennes, Tours, and Vannes, FranceSee the 8 sites

Where in France

  • CHU d AngersAngers, FranceTaking people
  • CHU de BrestBrest, FranceTaking people
  • CHD VendéeLa Roche-sur-Yon, FranceTaking people
  • Groupe Hospitalier Bretagne SudLorient, FranceTaking people
  • CHU de Nantes - Hôtel DieuNantes, FranceTaking people
  • CHU de RennesRennes, FranceTaking people
  • CHU de ToursTours, FranceTaking people
  • CH Bretagne AtlantiqueVannes, FranceTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University Hospital, Brest
Trial code
NCT06923202
Record updated
1 June 2026
Original description
Alloknesia is defined as pruritus (= itching) triggered by light mechanical stimuli, which are responsible for the perception of light touch under physiological conditions, but which are perceived as pruritic under pathological conditions. Alloknesia occurs mainly in the context of chronic pruritus. Consequently, patients suffering from chronic pruritus frequently perceive light touch sensations as pruritic, which can be particularly unpleasant and alter human interactions and quality of life on a daily basis. However, the epidemiology and burden of alloknesia have never been studied, whatever the cause of chronic pruritus.Atopic dermatitis is one of the main diseases causing chronic itching, and patients frequently complain of alloknesia. In this study, the investigators are studying the frequency of alloknesia in patients with atopic dermatitis and measuring the consequences of alloknesia in these patients.Read full original descriptionShow less

Study of Alloknesia in Atopic Dermatitis

Alloknesia is defined as pruritus (= itching) triggered by light mechanical stimuli, which are responsible for the perception of light touch under physiological conditions, but which are perceived as pruritic under pathological conditions. Alloknesia occurs mainly in the context of chronic pruritus. Consequently, patients suffering from chronic pruritus frequently perceive light touch sensations as pruritic, which can be particularly unpleasant and alter human interactions and quality of life on a daily basis. However, the epidemiology and burden of alloknesia have never been studied, whatever the cause of chronic pruritus.Atopic dermatitis is one of the main diseases causing chronic itching, and patients frequently complain of alloknesia. In this study, the investigators are studying the frequency of alloknesia in patients with atopic dermatitis and measuring the consequences of alloknesia in these patients.

Inclusion: Age ≥18 years; No opposition from the patient; Diagnosis of atopic dermatitis more than 6 months old.

Exclusion: Patients who are physically or mentally unable to complete the questionnaires; Patients on systemic treatment for 1 month or more; Refusal to participate; Patients under legal protection (guardianship, curatorship); Patients under court protection.

ClinicalTrials.gov NCT06923202