NCT06923917Not yet recruiting
European Registry of Acutely Decompensated Pulmonary Arterial Hypertension
European Registry of Acutely Decompensated Pulmonary Hypertension
Source: ClinicalTrials.gov · Last updated 24 Nov 2025
Brief summary (registry, in English)
Acute decompensation of pulmonary hypertension (PH) is associated with a very unfavorable short-term prognosis. However, the development of circulatory support techniques and the possible use of emergency transplantation in recent years has significantly changed the management of patients with refractory right ventricular failure. Nonetheless, there are significant disparities in the management of these patients depending on the organization of the care pathway, the rules for graft allocation, and access to circulatory support across European countries. Moreover, the implementation of these new therapeutic strategies requires the identification of effective prognostic factors and the development of new monitoring techniques. The objective of this collaborative clinical research project is to study the prognostic implications of acute decompensated right heart failure associated with PAH based on a large-scale European multicenter approach using a prospective analysis of clinical, biological, and echocardiographic data.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 4 Apr 2025
- Start date
- 1 Dec 2025
- Primary completion date
- 1 Dec 2028
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- NCT number
- NCT06923917
What you commit to
- Study type: Observational
- Planned participants: 200
- From 1 Dec 2025 to the primary completion date, 1 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with non-group 1 pulmonary hypertension
- Shock due to a cause other than right heart failure
- Person under psychiatric care
Other
- Person unable to provide written informed consent (person deprived of liberty by judicial or administrative decision)
- Person who is the subject of a legal protection measure (tutelage, guardianship, safeguard of justice)
- Patient's objection to the use of their data
Who the study is looking for
- Patients with established diagnosis of pulmonary arterial hypertension (group 1) according to the 2022 ESC/ERS guidelines.
- Worsening of clinical signs of right heart failure in the month prior to hospital admission requiring the use of:
- intravenous diuretic therapy for ≥ 2 days
- or inotropes
- or vasopressors
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Assistance Publique Hopitaux De Paris Coordinator of this site? Confirm its status | Le Kremlin-Bicetre | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.