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Eye Imaging and Blood Markers for Early Detection of Alzheimer's Disease

Studies eye imaging and blood markers to detect Alzheimer's disease early in adults over 50.

Key facts

Who runs it
Peking University First Hospital
Where
Beijing, ChinaSee the site
Trial code
Registry title
Multimodal Ophthalmic Imaging and Plasma Biomarkers for the Early Detection of Alzheimer's Disease
Status
Recruiting
People taking part
200 people, planned
Started
19 Mar 2025
Expected to end
31 Aug 2027
Type of study
Observational
Treatments tested
  • Multimodal Ophthalmic Imaging and plasma biomarker
Record updated
29 September 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people aged 50 or older who have Alzheimer's disease, mild or subjective memory and thinking decline, or normal thinking. Eye imaging and blood tests will be used.

Age
50 years or older
Sex
Men and women
Disease stage
Alzheimer's disease (AD), mild cognitive decline (MCI), subjective cognitive decline (SCD), or cognitively normal (CN)

Main reasons for not taking part

  • Other brain or nerve disorders or body-wide diseases that may cause memory and thinking problems
  • Cannot cooperate with memory and thinking tests
  • Refuses to give a blood sample

The registry criteria, word for word

Show all 6 criteriaShow less

Who can take part

  • Male or female participants aged ≥ 50 years
  • Participants diagnosed with Alzheimer's Disease (AD), mild cognitive decline (MCI), subjective cognitive decline (SCD), or cognitively normal (CN)
  • Signed informed consent form

Who cannot take part

  • Presence of other neurological disorders and systemic diseases that may cause cognitive impairment
  • Inability to cooperate with cognitive assessments
  • Refusal to undergo blood sampling

Where in China

  • Peking University First HospitalBeijing, ChinaContact: Yong an Prof.SunTaking people

About the trial

What the trial wants to find out

With the accelerating global aging population, dementia has become a pressing worldwide issue. This project aims to identify specific plasma biomarkers and ocular indicators for the early detection of Alzheimer's disease (AD).

The group in the trial

  • Different stages of Alzheimer's disease

    Treatment: Multimodal Ophthalmic Imaging and plasma biomarker

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Multimodal Ophthalmic Imaging and Plasma Biomarkers for the Early Detection of Alzheimer's Disease
Plain-language title
Eye Imaging and Blood Markers for Early Detection of Alzheimer's DiseaseGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
29 September 2026