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NCT06929507Recruiting

Impact of Intravitreal Faricimab on Renal Function in Diabetic Patients

The Impact of Intravitreal Injection of Anti-vascular Endothelial Growth Factor Faricimab on Renal Function in Patients With Diabetes Mellitus

Source: ClinicalTrials.gov · Last updated 24 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

This study aims to investigate the impact of intravitreal injection of anti-vascular endothelial growth factor (anti VEGF) Faricimab on renal function of diabetic patients. Faricimab is a new anti-VEGF drug which inhibits both VEGF-A and Ang-2 and it is used for the treatment of diabetic macular edema and neovascular age related macular degeneration. It is known that previous anti-VEGF agents has systematic absorption and may cause deterioration in renal function of the patients. However, the effect of Faricimab on kidney function has not been investigated yet. Taking into account that Ang-2 has destructive effect on kidneys, the investigation of the effect of its inhibition in diabetic patients who have already renal function deterioration may provide a valuable information in scientific community.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
60 (estimated)
First submitted
7 Apr 2025
Start date
10 Mar 2025
Primary completion date
10 Mar 2026
Lead sponsor
University Hospital, Alexandroupolis
NCT number
NCT06929507

What you commit to

  • Study type: Interventional
  • Planned participants: 60
  • From 10 Mar 2025 to the primary completion date, 10 Mar 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous renal transplantation Patients under hemodialysis

Other illness

  • Patients with end stage renal disease
  • Patients with other retinal disorders

Other

  • Pregnancy

Who the study is looking for

  • Patients with diabetes
  • Patients with DME or nAMD or macular edema secondary to retinal vein occlusion
  • Patients already receiving nephroprotective drugs

Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Hospital of Alexandroupolis
Coordinator of this site? Confirm its status
AlexandroupoliGreeceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.