NCT06929507Recruiting
Impact of Intravitreal Faricimab on Renal Function in Diabetic Patients
The Impact of Intravitreal Injection of Anti-vascular Endothelial Growth Factor Faricimab on Renal Function in Patients With Diabetes Mellitus
Source: ClinicalTrials.gov · Last updated 24 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to investigate the impact of intravitreal injection of anti-vascular endothelial growth factor (anti VEGF) Faricimab on renal function of diabetic patients. Faricimab is a new anti-VEGF drug which inhibits both VEGF-A and Ang-2 and it is used for the treatment of diabetic macular edema and neovascular age related macular degeneration. It is known that previous anti-VEGF agents has systematic absorption and may cause deterioration in renal function of the patients. However, the effect of Faricimab on kidney function has not been investigated yet. Taking into account that Ang-2 has destructive effect on kidneys, the investigation of the effect of its inhibition in diabetic patients who have already renal function deterioration may provide a valuable information in scientific community.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 7 Apr 2025
- Start date
- 10 Mar 2025
- Primary completion date
- 10 Mar 2026
- Lead sponsor
- University Hospital, Alexandroupolis
- Diseases
- Macular degeneration, Diabetic eye disease
- NCT number
- NCT06929507
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 10 Mar 2025 to the primary completion date, 10 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous renal transplantation Patients under hemodialysis
Other illness
- Patients with end stage renal disease
- Patients with other retinal disorders
Other
- Pregnancy
Who the study is looking for
- Patients with diabetes
- Patients with DME or nAMD or macular edema secondary to retinal vein occlusion
- Patients already receiving nephroprotective drugs
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital of Alexandroupolis Coordinator of this site? Confirm its status | Alexandroupoli | Greece | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.