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Taking people in CanadaNo phase

Tests heat-based ablation for small, low-risk thyroid cancer

Tests radiofrequency ablation, a heat treatment, in adults with small thyroid cancer.

Key facts

Who runs it
University Health Network, Toronto
Where
Toronto, CanadaSee the site
Trial code
Registry title
The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer
Status
Recruiting
People taking part
40 people, planned
Started
20 Apr 2023
Planned end
31 Dec 2025
Type of study
Interventional
Treatments tested
  • Radiofrequency ablation
Record updated
16 April 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with a small thyroid nodule, 2 cm (0.8 in) or less, that was graded Bethesda 5/6. It tests treating the nodule with radiofrequency ablation.

Age
18 to 100 years
Sex
All sexes can join.
Disease stage
A thyroid nodule of 2 cm or less in size, graded Bethesda 5/6.
Earlier treatment
People previously treated for thyroid cancer cannot join.

Main reasons for not taking part

  • Under 18 years old
  • Pregnant women
  • Any concern for invasive or metastatic thyroid cancer
  • Previously treated for thyroid cancer

The registry criteria, word for word

Show all 9 criteriaShow less

Who can take part

  • Patients with:
  • Nodule less than or equal to 2cm in size; Specifically: Bethesda 5/6
  • Their age is ≥18 years and ≤100 years
  • Able to provide written consent
  • Able to attend required follow-ups as per the protocol

Who cannot take part

  • Previously treated for thyroid cancer
  • Any concern for invasive or metastatic thyroid cancer
  • Patients <18 years old
  • Pregnant women

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 100 years old?

Where in Canada

  • University Health NetworkToronto, CanadaContact: Ilhaan AbdulleTaking people

About the trial

What the trial wants to find out

The goal of this clinical trial is to test radiofrequency ablation (RFA) in thyroid cancers ≤2 cm in diameter. The main question it aims to answer is:

Read full original descriptionShow less

• What is the feasibility of RFA use for low-risk thyroid cancers (≤2 cm)?

Participants will undergo a set of pre-procedural scans of the target thyroid nodule and undergo the RFA procedure/intervention. Then, participants will partake in three follow-up appointments at 4 weeks, 6 months, and 12 months post-procedure as per standard of care.

The group in the trial

  • InterventionTreatment being tested

    Participants receive RFA intervention for thyroid nodule.

    Treatment: Radiofrequency ablation

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Thermo-Ablation With Radiofrequency Medical Technologies to Treat Thyroid Cancers
Plain-language title
Tests heat-based ablation for small, low-risk thyroid cancerGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Fit questions
Built from NCT06929650, who can take part
Record updated
16 April 2025