Testing language and thinking training for chronic aphasia after stroke
Tests combined word-finding and thinking-skills training in adults with chronic aphasia after stroke.
Plain-language title generated from the registry record
Registry title: Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
Key facts
- Where
- Toulouse, FranceSee the site
Where in France
- University Hospital of ToulouseToulouse, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Toulouse
- Trial code
- NCT06930131
- Record updated
- 5 November 2026
- Original description
The postulate of this study is that rehabilitation combining linguistic and metacognitive training will result in a significant improvement in language performance correlated with changes in functional cerebral connectivity networks. In addition, it could potentiate the generalisation of effects to verbal and non-verbal communication skills, having a direct impact on patients' quality of life. This research is a prospective, randomized controlled, open-label, single-centre study. It is part of the management of patients with aphasia who have suffered a cerebral infarction and aims to evaluate the effect of combined language semantics/metacognition rehabilitation.Read full original descriptionShow less
Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia
The postulate of this study is that rehabilitation combining linguistic and metacognitive training will result in a significant improvement in language performance correlated with changes in functional cerebral connectivity networks. In addition, it could potentiate the generalisation of effects to verbal and non-verbal communication skills, having a direct impact on patients' quality of life. This research is a prospective, randomized controlled, open-label, single-centre study. It is part of the management of patients with aphasia who have suffered a cerebral infarction and aims to evaluate the effect of combined language semantics/metacognition rehabilitation.
Inclusion: First cerebral infarction; Chronic phase (> 3 months); Patient affiliated to a health insurance scheme; Usual french language; Severity score measures using the Boston Diagnostic Aphasia Examination battery scale corresponding to the mild or moderate level (score greater than or equal to 2).
Exclusion: Chronic alcohol or drug abuse; Cognitive impairment pre-existing stroke (CQI code > 3.4) (Law et al., 1995); Unstabilised psychiatric illness; Contraindication to undergoing brain MRI; Uncorrected sensory deficits; Diagnosed as having a progressive general pathology.