Tests MitoQ and ischemic conditioning for vascular health after stroke
Tests a supplement and a blood-flow device in stroke survivors aged 18 to 85.
Plain-language title generated from the registry record
Registry title: MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes
Key facts
- Where
- Milwaukee, United StatesSee the site
- Phase
- Phase 2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT06930638, who can take part
Where in United States
- Medical College of WisconsinMilwaukee, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Medical College of Wisconsin
- Trial code
- NCT06930638
- Record updated
- 25 September 2025
- Original description
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance. Preliminary data shows a single bout of ischemic conditioning or oral ingestion of an over-the-counter antioxidant supplement called MitoQ may improve vascular function and muscle activity in individuals post-stroke.Read full original descriptionShow less
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes (MITO Study)
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance. Preliminary data shows a single bout of ischemic conditioning or oral ingestion of an over-the-counter antioxidant supplement called MitoQ may improve vascular function and muscle activity in individuals post-stroke.
Inclusion: 18 - 85 years of age; Cortical or sub-cortical stroke ≥ 6 months ago with residual hemiparesis; Able to give informed consent and follow 2-step command; English Speaking.
Exclusion: Myocardial infarction or arrhythmia in the previous year; History of blood clots in the extremities or any condition in which compression of the thigh or transient ischemia is contraindicated (i.e., wounds in the leg); Chronic lasting symptoms (> 6 months) of severe COVID-19 (i.e., hospitalization); History of head trauma or concussion within the past 6 months; Comorbid neurological disorder; Peripheral vascular disease; Other significant medical condition likely to influence study or jeopardize safety as assessed by the Primary Investigator; Unable to stand from chair without physical assistance from another person (able to use assistive device); Resting SBP ≥180 mmHg or DBP ≥ 100 mmHg; Pregnant or breastfeeding.