Tests a non-invasive brain stimulation device for movement problems in Parkinson's disease
Tests a brain stimulation device aimed at the globus pallidus in people with Parkinson's disease.
Plain-language title generated from the registry record
Registry title: The Efficacy and Safety of Transcranial Temporal Interference Stimulation (tTIS) Targeting the Right Globus Pallidus Internus (GPi) for Motor Symptoms in Patients With PD
Key facts
- Where
- Hefei, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 80 years old?
Source: NCT06931483, who can take part
Where in China
- Anhui Medical UniversityHefei, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Yanghua Tian
- Trial code
- NCT06931483
- Record updated
- 17 April 2025
- Original description
To demonstrate that intervention targeting the right globus pallidus internus (GPi) using transcranial temporal interference stimulation can improve motor symptoms in patients with Parkinson's disease.Read full original descriptionShow less
The Efficacy and Safety of Transcranial Temporal Interference Stimulation (tTIS) Targeting the Right Globus Pallidus Internus (GPi) for Motor Symptoms in Patients With PD
To demonstrate that intervention targeting the right globus pallidus internus (GPi) using transcranial temporal interference stimulation can improve motor symptoms in patients with Parkinson's disease.
Inclusion: Meeting the diagnostic criteria for Parkinson's disease in China (2016 version), diagnosed as PD by two neurologists; Hoehn-Yahr stage 1.5-4; Age > 50 years old; No signs of moderate to severe depression: Beck Depression Inventory-II (BDI-II) score < 20; No signs of dementia: Mini-Mental State Examination (MMSE) score > 21; No change in medication regimen in the four weeks prior to enrollment; Right-handed.
Exclusion: Previous history of TMS or traditional TES treatment; Presence of non-MRI compatible metal implants in the body, such as deep brain stimulation devices, pacemakers or stents; History of other neuropsychiatric disorders; History of alcohol or drug abuse.