Checks tumor tissue levels of two proteins in bone cancers
Studies two proteins in tumor tissue from children with bone cancer.
Plain-language title generated from the registry record
Registry title: Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors
Key facts
- Where
- Cairo, EgyptSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for children, teenagers and young adults with osteosarcoma or Ewing sarcoma that has been confirmed under the microscope. It studies two tissue markers, KLF4 and KLF7.
- Age
- From 1 month to 39 years.
- Sex
- Males and females can join.
- Disease stage
- Osteosarcoma or Ewing sarcoma confirmed by tissue examination, in the bone or outside the bone. Both localized and metastatic disease can join.
- Biomarker or test result
- The record does not require a specific marker result. The trial measures Krüppel-like factors 4 and 7 in tissue.
Main reasons for not taking part
- A second malignant bone sarcoma
- Benign (non-cancerous) bone tumors
Read by machine on 12 November 2026.
Where in Egypt
- Ain Shams UniversityCairo, EgyptContact: Fatma EbeidTaking people
- Faculty of medicine Ain shams Research Institute-Clinical Research Center (MASRI-CRC)Cairo, EgyptContact: Fatma EbeidTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Ain Shams University
- Trial code
- NCT06935864
- Record updated
- 20 April 2025
- Original description
The current study is to assess the prognostic value of Krüppel-like factors 4 and 7 in bone tumors, and its role in the disease progression.Read full original descriptionShow less
The Prognostic Value of Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors
The current study is to assess the prognostic value of Krüppel-like factors 4 and 7 in bone tumors, and its role in the disease progression.
Inclusion: Age: children, young adolescents younger than 15 years, and young adults (15 to 39 years) Gender: Males and female. Histologically confirmed patients with skeletal or extra-skeletal OS or ES. Both localized and metastatic disease stages.
Exclusion: Patients with second malignant bone sarcoma. Patients with benign bone tumors.