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Taking peoplePhase 1

Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis

Key facts

Phase
Phase 1

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 42 and 75 years old?

Source: NCT06937528, who can take part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
University of Jordan
Trial code
NCT06937528
Record updated
22 April 2025
Original description
Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosisRead full original descriptionShow less

Knee Osteoarthrosis (KOA) in Jordanian Patients: a Phase I Dose-finding Study Using Extracellular Vesicles (EV) for Advanced Stage III and IV KOA

Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis

Inclusion: Severe KOA stage III or IV by Laurance \& Kellgren staging as judged by Posterioranterior (PA) Xray of the knee joint; Willing to participate by signing the informed consent.

Exclusion: Oral anticoagulants or heparin therapy; Heart failure or arrhythmia; Uncontrolled Diabetes Mellitus; Evidence of Infectious Diseases; Active infection; Malignancy; Sublaxation beyond 20 degrees of the bones of the knee joint; Body Mass Index > 35; Pregnancy; Anemia less than 11g/dl or thrombocytopenia less than 100,000 or leucopenia less than 3000; Unreliable patients; Non-resident in Jordan.

ClinicalTrials.gov NCT06937528