Tailored blood pressure treatment guided by cause, for adults with high blood pressure
Tests personalized blood pressure medicines and lifestyle advice in adults with high blood pressure.
Plain-language title generated from the registry record
Registry title: Etiological Classification-guided Individual Intervention in Primary Hypertension
Key facts
- Where
- Shanghai, ChinaSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06941935, who can take part
Where in China
- Department of Cardiology, Shanghai Tenth People's HospitalShanghai, ChinaNo longer taking part
- Shanghai Tenth People's HospitalShanghai, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shanghai 10th People's Hospital
- Trial code
- NCT06941935
- Record updated
- 24 April 2025
- Original description
Eligible participants will first undergo a 1-week home blood pressure diary and 24-hour ambulatory blood pressure assessment. After a confirmed diagnosis of hypertension, etiological subtyping will be performed. Based on the blood pressure evaluation results and etiological classification, the most appropriate antihypertensive medication will be selected. Simultaneously, a personalized lifestyle prescription will be provided according to the patient's individual circumstances. Following medication initiation, participants will continue to monitor their blood pressure through home diaries. Monthly evaluations will be conducted, and if blood pressure fails to reach the target value, medication adjustments will be made based on the blood pressure diary until target levels are achieved. This regimen will be maintained long-term.Read full original descriptionShow less
Etiological Classification-guided Individual Intervention in Primary Hypertension: An All-comer Registry Study
Eligible participants will first undergo a 1-week home blood pressure diary and 24-hour ambulatory blood pressure assessment. After a confirmed diagnosis of hypertension, etiological subtyping will be performed. Based on the blood pressure evaluation results and etiological classification, the most appropriate antihypertensive medication will be selected. Simultaneously, a personalized lifestyle prescription will be provided according to the patient's individual circumstances. Following medication initiation, participants will continue to monitor their blood pressure through home diaries. Monthly evaluations will be conducted, and if blood pressure fails to reach the target value, medication adjustments will be made based on the blood pressure diary until target levels are achieved. This regimen will be maintained long-term.
Inclusion: Age 18-65 years; Diagnosed primary hypertension (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg); signed informed consent.
Exclusion: Secondary hypertension or arrhythmias affecting blood pressure accuracy (e.g., atrial fibrillation); History of stroke or myocardial infarction; Comorbidities such as diabetes, chronic kidney disease (eGFR < 30 mL/min/1.73m²), coronary artery disease, heart failure, or serious valvular heart disease; Pregnancy, breastfeeding, or planning to become pregnant; Life expectancy < 1 year; Participation in another clinical trial.