Tests a numbing chest scope as first step for suspected malignant pleural effusion
Tests chest scope biopsy first in adults with suspected malignant pleural effusion.
Plain-language title generated from the registry record
Registry title: First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.
Key facts
- Where
- Athens, GreeceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 90 years old?
Source: NCT06946498, who can take part
Where in Greece
- Sotiria General Hospital of Thoracic DiseasesAthens, GreeceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National and Kapodistrian University of Athens
- Trial code
- NCT06946498
- Record updated
- 27 April 2025
- Original description
Non randomized study with two groups. The study group includes patients with suspected malignant pleural effusion, in whom the investigation of pleural effusion begins directly with pleural biopsy by Local Anesthesia Thoracoscopy (LAT).Read full original descriptionShow less
Local Anesthesia Thoracoscopy as a First Line Approach in the Diagnosis of Suspected Malignant Pleural Effusion: FLAT Trial.
Non randomized study with two groups. The study group includes patients with suspected malignant pleural effusion, in whom the investigation of pleural effusion begins directly with pleural biopsy by Local Anesthesia Thoracoscopy (LAT).
The Control Group includes patients who come to the same hospital and are treated with the Standard of Care (SOC) strategies were used. Efficacy of LAT, Sensitivity, Hospitalization, time to diagnosis and general safety and comfort of the groups' subjects will be assessed.
Inclusion: Undiagnosed pleural effusion with the character of a lymphocytic exudate.
Exclusion: Acute respiratory failure and/or Hypercapnia; Empyema; Transudate pleural effusion; Central airway obstruction by tumor; Existence of extensive adhesions that do not allow the development of iatrogenic pneumothorax and the safe entry of the thoracoscope; Uncontrollable cough; Performance Status: 5.