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Checking Food Allergy by Food Challenge in Children With Eczema

Tests a food challenge to confirm food allergy in children under 6 with eczema.

Plain-language title generated from the registry record
Registry title: Frequency of Food Allergy Confirm by Oral Food Challenge Among Foods Avoidance in Atopic Dermatitis Children

Key facts

Where
Bangkok, ThailandSee the site

Where in Thailand

  • Siriraj HospitalBangkok, ThailandNo longer taking part

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Trial details

Who runs it
Mahidol University
Trial code
NCT06947252
Record updated
27 April 2025
Original description
Atopic dermatitis can be caused by several factors, including food allergy. Currently, the diagnosis of food allergy often performing skin tests and measuring specific IgE foods that many studies have shown that about 53% of children with atopic dermatitis have food sensitization, result in avoidance of food intake. But only 15% are confirmed to have a true food allergy, so the purpose of our study is to find the prevalence of food allergy in Thai children with atopic dermatitis who are avoiding some foods, using the oral food challenge to confirm the diagnosis to reduce unnecessary food avoidance and prevent complications from inappropriate dietary restrictionsRead full original descriptionShow less

Validation of Food Allergies in Pediatric Atopic Dermatitis Patients Practicing Food Avoidance

Atopic dermatitis can be caused by several factors, including food allergy. Currently, the diagnosis of food allergy often performing skin tests and measuring specific IgE foods that many studies have shown that about 53% of children with atopic dermatitis have food sensitization, result in avoidance of food intake. But only 15% are confirmed to have a true food allergy, so the purpose of our study is to find the prevalence of food allergy in Thai children with atopic dermatitis who are avoiding some foods, using the oral food challenge to confirm the diagnosis to reduce unnecessary food avoidance and prevent complications from inappropriate dietary restrictions

Inclusion: Age ≤ 6 years; Age ≤ 6 years with diagnosis of atopic dermatitis c; Now parent report them avoid at least 1 food of egg yolk, egg white, cow milk, peanut, wheat or soy.

Exclusion: Patients who had been treated with some other immunotherapy e.g. SCIT, OIT; Patients with delayed developmental problem or mental disorder; Specific IgE food > 95%PPV (73-74%PPV in wheat, soy); Patients with uncontrolled asthma/ atopic dermatitis; Patient use beta-blocker, ACEI, ARB; Patient who unable to follow up.

ClinicalTrials.gov NCT06947252