Tests counseling to reduce stigma in adults with HIV and depression in Malawi
Tests stigma reduction counseling alongside depression treatment in adults living with HIV.
Plain-language title generated from the registry record
Registry title: HIV-Mental Illness Stigma Reduction and Outcomes in Malawi
Key facts
- Where
- Mulanje and Salima, MalawiSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults living with HIV who take ART and have some signs of depression. It tests counseling that also targets stigma.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Living with HIV and having raised depression symptoms (PHQ-9 score of 5 or more)
- Earlier treatment
- Must be receiving ART (HIV treatment) at Salima or Mulanje District Hospital
Main reasons for not taking part
- Pregnant women
- Severe mental illness
- Severe physical illness
This trial only enrols participants living with HIV. The registry sentence this rests on: Living with HIV and receiving ART at Salima or Mulanje District Hospital
Read by machine on 9 November 2026.
Where in Malawi
- Mulanje District HospitalMulanje, MalawiNo longer taking part
- Salima District HospitalSalima, MalawiNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Pennsylvania
- Trial code
- NCT06951542
- Record updated
- 10 June 2026
- Original description
The overall aim of this study is to assess the acceptability, feasibility, fidelity, and effectiveness of a depression treatment intervention augmented with counseling to address stigma. Using a multiple-baseline design, 200 depressed adults living with HIV will be enrolled in the trial. Participant surveys and abstracted clinical data related to HIV and depression care will assess the effectiveness of the intervention.Read full original descriptionShow less
Improving HIV and Depression Outcomes by Reducing HIV-Mental Illness Stigma in Salima and Mulanje Districts: Pilot Trial
The overall aim of this study is to assess the acceptability, feasibility, fidelity, and effectiveness of a depression treatment intervention augmented with counseling to address stigma. Using a multiple-baseline design, 200 depressed adults living with HIV will be enrolled in the trial. Participant surveys and abstracted clinical data related to HIV and depression care will assess the effectiveness of the intervention.
Inclusion: Living with HIV and receiving ART at Salima or Mulanje District Hospital; Adult (18+ years); Elevated depressive symptoms (PHQ-9 Score ≥5).
Exclusion: Severe mental or physical illness; Pregnant women.