Tests low-dose ketamine during surgery for endometriosis pain
Tests low-dose ketamine given during keyhole surgery in adults with endometriosis.
Plain-language title generated from the registry record
Registry title: Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine
Key facts
- Where
- Bern, SwitzerlandSee the site
- Phase
- Phase 4
Where in Switzerland
- Inselspital BernBern, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Insel Gruppe AG, University Hospital Bern
- Trial code
- NCT06951802
- Record updated
- 30 April 2025
- Original description
RCT comparing intraoperative administration of low-dose ketamine during laparoscopic endometriosis operation and the postoperative pain outcomeRead full original descriptionShow less
Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine A Single-Centre, Prospective, Randomized, Controlled Trial
RCT comparing intraoperative administration of low-dose ketamine during laparoscopic endometriosis operation and the postoperative pain outcome
Inclusion: Patients undergoing surgery for endometriosis operation requiring general anaesthesia at the Inselspital, Bern University Hospital, University of Bern, Department of gynaecology and obstetrics; Age ≥ 18 years; American Society of Anesthesiologist (ASA) physical status 1-3; Patients with known or suspected endometriosis; Written informed consent.
Exclusion: Myocardial infarction during the last 30 days prior to surgery; Liver disease; Known malignant hyperthermia; Cardiovascular instability or severe heart failure (New York Heart Association classification (NYHA) > III); Limited peripheral autonomic activity, hypersensitivity to ketamine or propofol or its components; Age < 18 years; ASA physical status ≥4; Higher-grade atrioventricular block without pacemaker; Severe hypovolemia or bradycardia; Uncontrolled hyper- or hypotension; Increased intracranial or increased intraocular pressure; Pregnancy; Rejection or lack of consent of the patient or relatives.