Taking people in United StatesPhase 4

Checks Eye Side Effects of Tivdak in Recurrent Cervical Cancer

Studies eye-related side effects of Tivdak in adults with returned cervical cancer.

Plain-language title generated from the registry record
Registry title: Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

Key facts

Where: Arlington, Atlanta, Augusta, Austin, Aventura, Billings, Bonita Springs, Bradenton, Brooklyn, Burnsville, Camden, Cape Coral, Centerville, Chardon, Charlottesville, Chicago, Cleveland, Columbus, Coral Springs, Dallas, Daytona Beach, Deerfield Beach, Denver, Duarte, Edina, Erie, Fleming Island, Fort Lauderdale, Fort Myers, Fort Worth, Harlingen, Houston, Indianapolis, Jackson, Kettering, Las Vegas, Louisville, Maple Grove, Maplewood, Mayfield Heights, McAllen, Mechanicsburg, Mentor, Miami, Miami Beach, Minneapolis, Monroeville, N. Venice, Naples, New Orleans, New York, Orange, Orlando, Palm Beach Gardens, Parma, Peoria, Phoenix, Pittsburgh, Port Charlotte, Portland, Providence, Richardson, Roanoke, Sarasota, Scottsdale, Sebring, Shreveport, Tempe, Tulsa, Voorhees Township, Waco, Wellington, Weslaco, West Palm Beach, Westlake, and Woodbury, United StatesSee the 129 sites
Phase: Phase 4

Where in United States

Texas Oncology - DFWArlington, United StatesTaking people
Emory University HospitalAtlanta, United StatesTaking people
Emory University Hospital MidtownAtlanta, United StatesTaking people
Grady Health System Correll PavilionAtlanta, United StatesTaking people
Grady Memorial Hospital Investigational Drug ServiceAtlanta, United StatesTaking people
The Emory ClinicAtlanta, United StatesTaking people
Winship Cancer InstituteAtlanta, United StatesTaking people
Georgia Cancer Center at Augusta UniversityAugusta, United StatesTaking people
Texas Oncology - Central SouthAustin, United StatesTaking people
Mount Sinai Comprehensive Cancer Center, AventuraAventura, United StatesTaking people
Intermountain Health Saint Vincent Regional HospitalBillings, United StatesTaking people
Intermountain Health West End Clinic- Gynecologic OncologyBillings, United StatesTaking people
Saint Vincent Regional Hospital- Cancer Centers of MontanaBillings, United StatesTaking people
Yellowstone Eye CareBillings, United StatesTaking people
Florida Cancer SpecialistsBonita Springs, United StatesTaking people
Florida Cancer SpecialistsBradenton, United StatesTaking people
Maimonides Medical CenterBrooklyn, United StatesTaking people
M Health Fairview Clinics and Specialty CenterBurnsville, United StatesTaking people
MD Anderson Cancer Center at CooperCamden, United StatesTaking people
Florida Cancer SpecialistsCape Coral, United StatesTaking people
Miami Valley Hospital SouthCenterville, United StatesTaking people
SCC at UH Geauga Medical CenterChardon, United StatesTaking people
University of VirginiaCharlottesville, United StatesTaking people
UVA Comprehensive Cancer CenterCharlottesville, United StatesTaking people
UVA Health Cancer Care PantopsCharlottesville, United StatesTaking people
Rush University Medical CenterChicago, United StatesTaking people
Rush University Medical Center, OphthalmologyChicago, United StatesTaking people
Cleveland ClinicCleveland, United StatesTaking people
Cleveland Clinic Fairview HospitalCleveland, United StatesTaking people
University Hospitals Cleveland Medical Center*Cleveland, United StatesTaking people
Ohio Health Arthur G.H. Bing - MD Cancer CenterColumbus, United StatesNot yet recruiting
OhioHealth Research InstituteColumbus, United StatesNot yet recruiting
Riverside Methodist HospitalColumbus, United StatesNot yet recruiting
Broward Health Coral SpringsCoral Springs, United StatesTaking people
Parkland Health & Hospital SystemDallas, United StatesTaking people
University of Texas Southwestern Medical CenterDallas, United StatesTaking people
University of Texas Southwestern Medical Center - Simmons Cancer CenterDallas, United StatesTaking people
University of Texas Southwestern Medical Center - William P. Clements, Jr., University HospitalDallas, United StatesTaking people
University of Texas Southwestern Medical Center-Zale Lipshy University HospitalDallas, United StatesTaking people
Florida Cancer SpecialistsDaytona Beach, United StatesTaking people
Broward Health NorthDeerfield Beach, United StatesTaking people
AdventHealth Hematology and Oncology DenverDenver, United StatesTaking people
AdventHealth Medical Group Gynecologic Oncology at PorterDenver, United StatesTaking people
City of Hope (City of Hope National Medical Center, City of Hope Medical Center)Duarte, United StatesTaking people
M Health Fairview Clinics and Surgery CenterEdina, United StatesTaking people
UPMC Hillman Cancer Center ErieErie, United StatesTaking people
Florida Cancer SpecialistsFleming Island, United StatesTaking people
Broward Health Imperial PointFort Lauderdale, United StatesTaking people
Broward Health Medical CenterFort Lauderdale, United StatesTaking people
Florida Cancer SpecialistsFort Myers, United StatesTaking people
University of Texas Southwestern Simmons Cancer Center - Fort WorthFort Worth, United StatesTaking people
Texas Oncology- Central SouthHarlingen, United StatesTaking people
Texas Oncology - Gulf CoastHouston, United StatesTaking people
Indiana University Health University HospitalIndianapolis, United StatesTaking people
Indiana University Melvin and Bren Simon Comprehensive Cancer CenterIndianapolis, United StatesTaking people
Sidney & Lois Eskenazi HospitalIndianapolis, United StatesTaking people
St. Dominic - Jackson Memorial HospitalJackson, United StatesTaking people
St. Dominic Gynecologic OncologyJackson, United StatesTaking people
Kettering Health Cancer CenterKettering, United StatesTaking people
Kettering Health Main CampusKettering, United StatesTaking people
Women's Cancer Center of NevadaLas Vegas, United StatesTaking people
Norton Cancer Institute, DowntownLouisville, United StatesTaking people
Norton Cancer Institute, St. Matthews CampusLouisville, United StatesTaking people
Norton HospitalLouisville, United StatesTaking people
Norton Women's and Children's HospitalLouisville, United StatesTaking people
M Health Fairview Clinics and Surgery CenterMaple Grove, United StatesTaking people
M Health Fairview St. John's HospitalMaplewood, United StatesTaking people
Cleveland Clinic - Hillcrest HospitalMayfield Heights, United StatesTaking people
Texas Oncology -Central SouthMcAllen, United StatesTaking people
PinnacleHealth Women´s Cancer Center (Ortenzio Cancer Center)Mechanicsburg, United StatesTaking people
SCC at Lake University (LUSCC)Mentor, United StatesTaking people
HCA Mercy HospitalMiami, United StatesTaking people
Mount Sinai Comprehensive Cancer CenterMiami Beach, United StatesTaking people
Mount Sinai Medical Center of Florida, Inc.Miami Beach, United StatesTaking people
M Health Fairview Clinics and Surgery CenterMinneapolis, United StatesTaking people
UPMC Vision InstituteMonroeville, United StatesTaking people
Florida Cancer SpecialistsN. Venice, United StatesTaking people
Florida Cancer SpecialistsNaples, United StatesTaking people
University Medical Center New OrleansNew Orleans, United StatesTaking people
Columbia University Medical Center - Herbert Irving PavilionNew York, United StatesNot yet recruiting
IP Address: Columbia University Medical Center/New York Presbyterian Hospital Research PharmacyNew York, United StatesNot yet recruiting
UH Minoff Health Center/Chagrin Highlands- Seidman Cancer CenterOrange, United StatesTaking people
AdventHealthOrlando, United StatesTaking people
AdventHealth Gynecologic OncologyOrlando, United StatesTaking people
AdventHealth Orlando Infusion CenterOrlando, United StatesTaking people
Orlando Health Ambulatory Care CenterOrlando, United StatesTaking people
Orlando Health Cancer InstituteOrlando, United StatesTaking people
Orlando Health Orlando Regional Medical CenterOrlando, United StatesTaking people
Orlando Health Winnie Palmer Hospital for Women & BabiesOrlando, United StatesTaking people
Florida Cancer SpecialistsPalm Beach Gardens, United StatesTaking people
Parma - Seidman Cancer CenterParma, United StatesTaking people
Illinois Eye CenterPeoria, United StatesTaking people
OSF Saint Francis Medical Center (OSF SFMC)Peoria, United StatesTaking people
HonorHealth Cancer Care - Biltmore - AZCCC ImagingPhoenix, United StatesTaking people
HonorHealth Cancer Care - Biltmore - HonorHealth Research PharmacyPhoenix, United StatesTaking people
HonorHealth Research Institute (Arizona Center for Cancer Care) - HonorHealth Cancer Care -BiltmorePhoenix, United StatesTaking people
Sonora Quest Laboratories, LLCPhoenix, United StatesTaking people
South West Medical Imaging (SMIL)Phoenix, United StatesTaking people
University Ear, Nose, & Throat Eye & Ear InstitutePittsburgh, United StatesTaking people
University Ear, Nose, & Throat SpecialistsPittsburgh, United StatesTaking people
UPMC Vision Institute - MercyPittsburgh, United StatesTaking people
UPMC Vision Institute ShadysidePittsburgh, United StatesTaking people
UPMC-Magee Womens HospitalPittsburgh, United StatesTaking people
Florida Cancer SpecialistsPort Charlotte, United StatesTaking people
OHSUPortland, United StatesTaking people
Women & Infant´s Hospital Infusion CenterProvidence, United StatesTaking people
Women & Infants Hospital of Rhode IslandProvidence, United StatesTaking people
Women & Infants Hospital of Rhode Island/The Program in Women´s Oncology - ClinicProvidence, United StatesTaking people
University of Texas Southwestern Simmons Cancer Center - Richardson/PlanoRichardson, United StatesTaking people
Carilion Clinic Gynecologic OncologyRoanoke, United StatesTaking people
Florida Cancer SpecialistsSarasota, United StatesTaking people
Schwartz Laser Eye CenterScottsdale, United StatesTaking people
Virginia G. Piper Cancer Pharmacy - HonorHealth Research PharmacyScottsdale, United StatesTaking people
Florida Cancer SpecialistsSebring, United StatesTaking people
Trials365, LlcShreveport, United StatesTaking people
Willis Knighton Physician Network - Hematology/OncologyShreveport, United StatesTaking people
Willis Knighton Physician Network/Gynecologic Oncology AssociatesShreveport, United StatesTaking people
Willis-Knighton Cancer CenterShreveport, United StatesTaking people
WK Eye Institute NorthShreveport, United StatesTaking people
HonorHealth Cancer Care - Tempe - AZCCC ImagingTempe, United StatesTaking people
HonorHealth Research Institute (Arizona Center for Cancer Care) - HonorHealth Cancer Care - TempeTempe, United StatesTaking people
Oklahoma Cancer Specialists and Research Institute, LLCTulsa, United StatesTaking people
MD Anderson Cancer Center at CooperVoorhees Township, United StatesTaking people
Texas Oncology - Central SouthWaco, United StatesTaking people
Florida Cancer SpecialistsWellington, United StatesTaking people
Texas Oncology - Central SouthWeslaco, United StatesTaking people
Florida Cancer SpecialistsWest Palm Beach, United StatesTaking people
SCC at St. John's Medical CenterWestlake, United StatesTaking people
M Healt Fairview - Woodwinds HospitalWoodbury, United StatesTaking people

Questions to ask the study team

How often do I need to come in, and for how long each time?
Are travel costs paid?
Can I keep my own doctor?
What happens if I want to stop?

Print a page for my doctor

Trial details

Who runs it: Pfizer
Trial code: NCT06952660
Record updated: 5 November 2026
Original description: TIVDAK is used for the treatment of cervical cancer that has come back after chemotherapy. Chemotherapy is a treatment that uses medicines to stop the growth of cancer cells. This is done either by killing the cells or by stopping them from growing. The purpose of this study is to learn about possible side effects of TIVDAK, specially to any side effect that is related to the eye. A side effect is anything a medicine does to your body that is not part of how the medicine treats disease.Read full original descriptionShow less
A PROSPECTIVE LOW-INTERVENTIONAL PHASE 4 SINGLE ARM STUDY OF OCULAR ASSESSMENTS IN PATIENTS TREATED WITH TIVDAK® IN RECURRENT OR METASTATIC CERVICAL CANCER
TIVDAK is used for the treatment of cervical cancer that has come back after chemotherapy. Chemotherapy is a treatment that uses medicines to stop the growth of cancer cells. This is done either by killing the cells or by stopping them from growing. The purpose of this study is to learn about possible side effects of TIVDAK, specially to any side effect that is related to the eye. A side effect is anything a medicine does to your body that is not part of how the medicine treats disease.
* This study is seeking for participants who: Are willing to take all the required eye tests * Have not received TIVDAK before * Do not have any active eye issues.
Participants will receive TIVDAK once every 3 weeks as an infusion that will be injected into the vein. Participants will visit an eye care provider at 3 stages:
* before starting the treatment, * before each of the first 9 infusions * then monthly for 3 months after they stop taking TIVDAK. Treatment with TIVDAK will continue until it is not working anymore against the participant's cancer.
Inclusion: Must have recurrent or metastatic cervical cancer with disease progression on or after chemotherapy; Treating physician has determined that treatment with Tivdak is appropriate for the participant according to US Prescribing Information; Must sign an informed consent form indicating that the participant understands the purpose and procedures required for the study and are willing to participate; Must be willing to undergo repeated ocular assessments as required by the study and regular clinic visits according to local standard practice of the study site; Must agree to use effective contraception according to the US Prescribing Information.
Exclusion: Previous treatment with Tivdak; Previous administration of an investigational drug within 30 days; Active ocular disease at baseline per investigator assessment; Any medical or psychiatric condition including recent (within the past year) or active suicidal ideation/behavior or laboratory abnormality that may, in the investigator'.
ClinicalTrials.gov NCT06952660