Comparing two anesthesia methods during pancreas surgery for low blood pressure
Compares general anesthesia with combined general and epidural anesthesia in adults having pancreatic surgery.
Plain-language title generated from the registry record
Registry title: Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia
Key facts
- Where
- Mexico City, MexicoSee the site
Where in Mexico
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico City, MexicoTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
- Trial code
- NCT06953193
- Record updated
- 1 April 2026
- Original description
This randomized clinical trial compares the hemodynamic effects of general anesthesia versus combined general anesthesia (thoracic epidural) in patients undergoing pancreatoduodenectomy. The primary aim is to assess the incidence of intraoperative hypotension and related adverse events. Secondary outcomes includes vasopressor requirements, transfusion needs, postoperative complications, intensive care unit admission, hospital length of stay, and mortality.Read full original descriptionShow less
Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia
This randomized clinical trial compares the hemodynamic effects of general anesthesia versus combined general anesthesia (thoracic epidural) in patients undergoing pancreatoduodenectomy. The primary aim is to assess the incidence of intraoperative hypotension and related adverse events. Secondary outcomes includes vasopressor requirements, transfusion needs, postoperative complications, intensive care unit admission, hospital length of stay, and mortality.
Inclusion: Signed written informed consent; Patients scheduled for elective pancreatoduodenectomy at National Institute of Medical Sciences and Nutrition Salvador Zubirán; No contraindications for neuroaxial anesthesia (epidural catheter placement), including:; Generalized or localized infection at the puncture site; Thrombocytopenia; Coagulation disorders; Intracranial hypertension; Patient refusal.
Exclusion: Age under 18 years; Pregnancy; Inability to randomize the case due to specific circumstances (such as contraindications to epidural use), resulting in non-eligibility based on participation criteria.