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Effectiveness of Muscle Energy Techniques and Mulligan Mobilization Along With Conventional Physical Therapy in Knee Joint Osteoarthritis Patients

Key facts

Who runs it
Khyber Medical University Peshawar
Where
Pakistan3 sites in 1 countryChoose a country to see its sites
Trial code
Status
Completed
People taking part
24 people enrolled
Started
1 Apr 2025
Ended
28 Nov 2025
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Mulligan Mobilization
  • Muscle Energy Technique (MET)
Record updated
8 January 2026

Who can take part

Age
40 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 12 criteriaShow less

Who can take part

  • Diagnosed cases of osteoarthritis (Grade 1 to 3)
  • X-ray showing Grades I to III on Kellgren Lawrence scale of Osteoarthritis
  • Residents of Peshawar verified via NADRA CNIC
  • Both genders will be included with unilateral or bilateral knee involvement
  • Age group 40 and above
  • Duration of Knee pain for more than 3 months

Who cannot take part

  • History of any previously known neurological conditions i.e. stroke, peripheral neuropathy
  • Recent under gone surgery
  • Suspicious of malignancy around the knee joint
  • Significant comorbid diseases and disabilities are excluded from the study
  • Fractures in treatment limb
  • Recent Intra-articular injection

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

This study aims to evaluate the effectiveness of integrating Muscle Energy Technique (MET) and Mulligan Mobilization with conventional physical therapy in the management of knee osteoarthritis (OA), with a specific focus on improving hamstring flexibility and reducing functional limitations. The findings will help inform clinical decision-making and enhance patient outcomes in OA rehabilitation.

The 2 groups in the trial

  • Intervention GroupTreatment being tested

    Participants in this group will receive Mulligan Mobilization combined with Conventional Physical Therapy. Mulligan Mobilization includes medial and lateral tibial glides using a Mulligan belt. Each session will consist of 3 sets of 10 repetitions, administered 5 days a week for 3 weeks. In addition, patients will undergo standard conventional physical therapy exercises such as quadriceps strengthening, straight leg raising, and stretching exercises. Each treatment session will last 30 minutes.

    Treatment: Mulligan Mobilization

  • Control GroupExisting treatment, for comparison

    Participants in this group will receive Muscle Energy Technique (MET) targeting the hamstring muscles, in combination with Conventional Physical Therapy. The MET will follow a post-isometric relaxation approach, using both direct and indirect methods depending on patient condition. Each isometric contraction will be held for 10 seconds, followed by a 20-second stretch, repeated for 3 sets. Therapy will be conducted 5 days a week over a 3-week period. Each session will last 30 minutes. The same conventional physical therapy regimen as the intervention group will be applied.

    Treatment: Muscle Energy Technique (MET)

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Effectiveness of Muscle Energy Techniques and Mulligan Mobilization Along With Conventional Physical Therapy in Knee Joint Osteoarthritis Patients: A Randomized Controlled Trial
Record updated
8 January 2026