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Video-guided mental and physical exercise for gait freezing in Parkinson's disease

Tests imagining movements plus exercise, done by video, in people with Parkinson's disease.

Plain-language title generated from the registry record
Registry title: Remote Mental Practice for Freezing of Gait in Parkinson's Disease

Key facts

Where
São Paulo, BrazilSee the site

Where in Brazil

  • University of Sao PauloSão Paulo, BrazilTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University of Sao Paulo General Hospital
Trial code
NCT06957405
Record updated
27 August 2025
Original description
This single-blind, randomized controlled trial investigates the effects of a remotely delivered intervention based on mental practice (MP) combined with physical practice (PP) on freezing of gait (FOG) severity in people with idiopathic Parkinson's disease (PD). Fifty participants will be randomly assigned to either the experimental group (MP + PP) or a control group (PP + stretching). The intervention consists of 10 video-supervised sessions over 6 weeks. Primary outcomes include the Rapid Turn Test and percentage of time spent with FOG (%FOG). Secondary outcomes include the New Freezing of Gait Questionnaire (NFOG-Q), Movement Disorders Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Parkinson's Disease Questionnaire-39 (PDQ-39), and Telephone Montreal Cognitive Assessment (T-MoCA). The study aims to demonstrate whether MP using Dynamic Neuro-Cognitive Imagery (DNI) techniques can effectively reduce FOG severity and improve motor and cognitive function in people with PD.Read full original descriptionShow less

Effects of a Remote Mental and Physical Practice Intervention on Freezing of Gait in People With Parkinson's Disease: a Randomized Controlled Trial

This single-blind, randomized controlled trial investigates the effects of a remotely delivered intervention based on mental practice (MP) combined with physical practice (PP) on freezing of gait (FOG) severity in people with idiopathic Parkinson's disease (PD). Fifty participants will be randomly assigned to either the experimental group (MP + PP) or a control group (PP + stretching). The intervention consists of 10 video-supervised sessions over 6 weeks. Primary outcomes include the Rapid Turn Test and percentage of time spent with FOG (%FOG). Secondary outcomes include the New Freezing of Gait Questionnaire (NFOG-Q), Movement Disorders Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Parkinson's Disease Questionnaire-39 (PDQ-39), and Telephone Montreal Cognitive Assessment (T-MoCA). The study aims to demonstrate whether MP using Dynamic Neuro-Cognitive Imagery (DNI) techniques can effectively reduce FOG severity and improve motor and cognitive function in people with PD.

Inclusion: Clinical diagnosis of idiopathic PD; Use of dopaminergic medication; Experiencing FOG (positive response to the first question of the New Freezing of Gait Questionnaire - NFOG-Q); Able to walk independently at home; Access to internet and video call device; Agree to participate in the study.

Exclusion: Other neurological disorders; Cognitive impairment, detectable through the Telephone Montreal Cognitive Assessment (T-MoCA, < 12); Severe cardiovascular and/or respiratory alterations; Uncorrected visual and/or auditory alterations; Inability to perform motor imageryT during the administration of the Kinesthetic and Visual Imagery Questionnaire - 20 (KVIQ-20, < 20).

ClinicalTrials.gov NCT06957405