Plant-based diet, exercise and probiotics in adults with type 2 diabetes
Tests a plant-based diet, exercise and probiotics in adults with type 2 diabetes.
Plain-language title generated from the registry record
Registry title: Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise
Key facts
- Where
- São Paulo, BrazilSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 45 and 70 years old?
Source: NCT06959043, who can take part
Where in Brazil
- Universidade de São Paulo (USP)São Paulo, BrazilTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Maria Elizabeth Rossi da Silva
- Trial code
- NCT06959043
- Record updated
- 18 May 2025
- Original description
The study evaluates the impact of a strict vegetarian diet combined with regular physical exercise and the use of probiotics on metabolic, inflammatory, and epigenetic parameters in patients with type 2 diabetes. It aims to determine the influence of these interventions on gut microbiota, glycemic control, body composition, insulin resistance, and quality of life.Read full original descriptionShow less
Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise
The study evaluates the impact of a strict vegetarian diet combined with regular physical exercise and the use of probiotics on metabolic, inflammatory, and epigenetic parameters in patients with type 2 diabetes. It aims to determine the influence of these interventions on gut microbiota, glycemic control, body composition, insulin resistance, and quality of life.
Inclusion: Have a medical diagnosis of type 2 diabetes for a maximum of 5 years; Be omnivorous; Have a Body Mass Index (BMI) ≥ 25 kg/m2 and < 40 kg/m2; Be between the ages of 45 and 70, both genders; Women should be in the postmenopausal stage; Use no more than three hypoglycemic medications in total; Have the availability for a four-week consecutive hospitalization at CSVN.
Exclusion: Be using insulin, anti-obesity medications, antibiotics, and/or probiotic supplements in the 2 months preceding data collection; Have limited mobility and a previous diagnosis of cardiopulmonary diseases; Report current or previous (within the past two months) diarrhea during screening; Have liver or kidney failure and uncontrolled endocrine disorders (hypothyroidism, hypogonadism, and adrenal insufficiency); Have eating disorders or have undergone bariatric surgery; Use of alcohol or tobacco.