Tests oxygen therapy in young people with diabetic kidney disease
Tests oxygen therapy in people aged 10 to 17 with diabetic kidney disease.
Key facts
- Who runs it
- Assiut University
- Where
- Asyut, EgyptSee the site
- Trial code
- Registry title
- Oxygen Therapy in Diabetic Kidney Disease
- Status
- Not yet recruiting
- People taking part
- 80 people, planned
- Started
- 1 Aug 2025
- Planned end
- 10 Aug 2026
- Type of study
- Interventional, 4 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Oxygen Therapy
- Record updated
- 6 May 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with diabetes and diabetic kidney disease who lose a lot of protein in the urine. It tests oxygen therapy.
- Age
- Over 18 years in the criteria. The registry header lists 10 to 17 years, which conflicts with this.
- Sex
- Men and women
- Disease stage
- Diabetic kidney disease with eGFR 30-90 mL/min/1.73m² and proteinuria >300 mg/day
- Biomarker or test result
- eGFR 30-90 mL/min/1.73m² and proteinuria >300 mg/day
Main reasons for not taking part
- Under 18 years of age
- Cardiovascular disease
- Chronic lung disease (COPD, pulmonary fibrosis)
- Other chronic disease affecting kidney function (lupus nephritis)
- Pregnancy or breastfeeding
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Diabetic male and female patients aged > 18 yrs with diabetic kidney disease (eGFR 30-90 mL/min/1.73m² and proteinuria >300 mg/day)
Who cannot take part
- Cardiovascular disease (thorough assessment of the patient's medical history (symptoms suggestive of CVD (e.g., chest pain, shortness of breath, fatigue), family history of CVD and risk factors (e.g., hypertension, hyperlipidemia, smoking). Physical Examination including blood pressure measurement, auscultation of heart sounds and assessment of peripheral pulses. Additional Diagnostic Tests: Stress test (stress ECG and stress echocardiography): Evaluate cardiac function under stress, which can help detect coronary artery disease or other CVD
- Chronic lung disease (COPD, pulmonary fibrosis …
- Other chronic disease affecting kidney function (lupus nephritis)
- Age < 18 yrs
- Pregnancy or lactation
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 10 and 17 years old?
Where in Egypt
- Assuit University hospitalsAsyut, EgyptContact: Mohamed Faisal Adawy, LecturerNo longer taking part
About the trial
What the trial wants to find out
Diabetic kidney disease (DKD) is the most significant cause of end-stage kidney disease (ESKD). Albuminuria, evolving from microalbuminuria to nephrotic-range proteinuria, is a clinical hallmark of diabetic nephropathy (DN). It develops in about a third of diabetic patients and is considered an independent risk factor in the progression of DN and for all-cause mortality.
The 4 groups in the trial
- Group AExisting treatment, for comparison
About 20 patients suffering from Diabetic kidney disease and will be treated by exposing to early morning air for 60 minutes (Early morning air" refers to the fresh, cool air found during the early hours of the day, (it's around 5-7 am, just before or after sunrise).
Treatment: Oxygen Therapy
- Group BExisting treatment, for comparison
About 20 patients suffering from Diabetic kidney disease and will be treated by exposing to oxygen by non- rebreather mask (We choose oxygen by non- rebreather mask and no other ways of oxygen delivery system because it is the only available cost effective and non-invasive oxygen delivery device that can provide high oxygen flow that is close enough to HBOT)
Treatment: Oxygen Therapy
- Group CExisting treatment, for comparison
About 20 patients suffering from Diabetic kidney disease and will be treated by exposing to hyperbaric oxygen therapy in a hyperbaric chamber at 2.5 ATA (atmospheres absolute) for 60 minutes per session (we choose 2.5 ATA hyperbaric oxygen therapy in a hyperbaric chamber (atmospheres absolute) for 60 minutes per session.
Treatment: Oxygen Therapy
- Group DExisting treatment, for comparison
About 20 patients suffering from Diabetic kidney disease and will receive standard diabetes and Diabetic kidney disease management
Treatment: Oxygen Therapy
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Oxygen Therapy in Diabetic Kidney Disease and Its Effect on Proteinuria and Blood Glucose Level
- Plain-language title
- Tests oxygen therapy in young people with diabetic kidney diseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06959485, who can take part
- Record updated
- 6 May 2025