Imaging Method to Find the Source of Clot-Caused Stroke
Tests a sodium fluoride PET scan to find plaques causing clot-related stroke.
Plain-language title generated from the registry record
Registry title: A Novel Method for Determination of Thromboembolic Stroke Origin
Key facts
- Where
- Summit, United StatesSee the site
- Phase
- Early phase 1
Where in United States
- Overlook Medical CenterSummit, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Atlantic Health System
- Trial code
- NCT06961604
- Record updated
- 8 May 2025
- Original description
Rupture of vulnerable carotid, vertebral, and intracranial arterial plaques results in thromboembolic stroke. Identification of these culprit lesions is an important component of post-stroke care. This study seeks to test the feasibility of NaF PET-CT to detect these plaques and alter patient care. Prior studies have shown a high degree of correlation between NaF PET+ lesions and high-risk plaque features on high resolution MRI, including mirocalcification, necrosis, and ulceration.Read full original descriptionShow less
A Novel Method for Determination of Thromboembolic Stroke Origin
Rupture of vulnerable carotid, vertebral, and intracranial arterial plaques results in thromboembolic stroke. Identification of these culprit lesions is an important component of post-stroke care. This study seeks to test the feasibility of NaF PET-CT to detect these plaques and alter patient care. Prior studies have shown a high degree of correlation between NaF PET+ lesions and high-risk plaque features on high resolution MRI, including mirocalcification, necrosis, and ulceration.