Computer-Based Cognitive Training by Telerehabilitation for Thinking Problems in Multiple Sclerosis
Tests online computer-based thinking training against in-person training in adults with multiple sclerosis.
Plain-language title generated from the registry record
Registry title: Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis
Key facts
- Where
- Verona, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06964581, who can take part
Where in Italy
- Azienda Ospedaliera Universitaria Integrata Verona - UOC di NeuroriabilitazioneVerona, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universita di Verona
- Trial code
- NCT06964581
- Record updated
- 9 May 2025
- Original description
Non-Inferiority Study, Post-Market Clinical Investigation with a Device, Single-Blind Randomized Controlled Trial in a Cohort of Patients Diagnosed with Multiple Sclerosis (MS).Read full original descriptionShow less
Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis: Proposal for an Integrated Cognitive Treatment in a Telematic Format
Non-Inferiority Study, Post-Market Clinical Investigation with a Device, Single-Blind Randomized Controlled Trial in a Cohort of Patients Diagnosed with Multiple Sclerosis (MS).
The aim of the study is to assess whether a computer-based cognitive treatment delivered via telerehabilitation produces effects from T0 to T1 that are not inferior to those of an in-person treatment on sustained attention in a cohort of patients with MS.
The secondary objective is to evaluate the effects of telerehabilitation compared to the same treatment delivered in person on attentional shifting, memory, executive functions, and daily functioning (including cognitive fatigue, quality of life, and mood) in patients with MS.
Inclusion: Diagnosis of relapsing-remitting multiple sclerosis (RRMS), or primary progressive (PPMS) or secondary progressive (SPMS), defined by at least 3-6 months; Age between 18 and 65 years; Expanded Disability Status Scale (EDSS) between 3 and 5 to include patients with overall neurological disability from mild to moderate; Presence of one or more of the following cognitive disorders (reported by the patient and subsequently confirmed through the Oxford Cognitive Screen-OCS):; Memory disorders; Attention disorders; Executive function disorders; Availability of internet at the patient's home necessary for the tele-rehabilitation procedures; Adequate visual and auditory abilities to use the rehabilitation device.
Exclusion: Alcohol and/or drug abuse; Presence of other neurological conditions; Psychiatric disorders in medical history; Presence of uncorrected severe visual deficits.