Tests a broccoli-derived supplement in adults with overweight or obesity
Tests a broccoli-derived pill against placebo in adults with overweight or obesity.
Plain-language title generated from the registry record
Registry title: Chronic Intervention With Sulforaphane-Smart® in Overweight and Obese Adults
Key facts
- Where
- Murcia, SpainSee the site
- Phase
- Early phase 1
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 20 and 45 years old?
Source: NCT06964659, who can take part
Where in Spain
- Edificio Pleyades-Vitalys 5ª y 6ª planta, Campus Universitario, EspinardoMurcia, SpainNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mª Jesús Periago
- Trial code
- NCT06964659
- Record updated
- 9 May 2025
- Original description
The Sulforaphane-Smart® formula is a pill, patented by the company INGREDALIA, prepared with broccoli by-products which have been concentrated and enriched in glucosinolates/isothiocyanates (GLS/ITCs).Read full original descriptionShow less
Sulforaphane-Smart® on Lipid and Glucose Metabolism, Inflammation, Adiposity and Microbiome of Overweight Adults "SANO"
The Sulforaphane-Smart® formula is a pill, patented by the company INGREDALIA, prepared with broccoli by-products which have been concentrated and enriched in glucosinolates/isothiocyanates (GLS/ITCs).
The goal of this intervention study is to evaluate if the chronic consumption of GSL/ITC (Sulforaphane Smart® formula) could modulate the biomarkers related to chronic inflammation, oxidative stress and gut microbiota in overweight and obese volunteers.
In order to reach this goal, the volunteers will take daily the Sulforaphane Smart® formula during 12 weeks (total of 84 days). Anthropometric measurements will be taken and biological samples of blood, urine and feces will be collected at the beginning of the intervention (initial time), after six weeks of the intervention (Time 6 weeks) and at the end of the intervention (Time 12 weeks).
Inclusion: BMI: overweight and obese (BMI 25-34,9 Kg/m2); No digestive or intestinal diseases; Age between 20 and 45 years old; Not having antibiotics during the previous three months; Not having pharmacological treatment; Not being smokers; Not following restrictive diets (vegetarian/vegan diet) or nutritional supplement.
Exclusion: Having antibiotics during the previous three months; Digestive or intestinal diseases; Age different from that required; BMI: low and normal weight; Having pharmacological treatments; Following restrictive diets (vegetarian/vegan diet) or nutritional supplement; Smoker.