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Testing a modified Pap test to encourage cervical cancer screening

Tests a changed Pap test ending in women aged 25 and older.

Plain-language title generated from the registry record
Registry title: Ameliorated Pap Tests and Cervical Cancer Screening Participation

Key facts

Where
Douliu, Hsinchu, and Taipei, TaiwanSee the 5 sites

Where in Taiwan

  • National Taiwan University Hospital Yunlin BranchDouliu, TaiwanTaking people
  • National Taiwan University Hospital Hsin Chu BranchHsinchu, TaiwanTaking people
  • National Taiwan University Cancer CenterTaipei, TaiwanTaking people
  • National Taiwan University HospitalTaipei, TaiwanTaking people
  • National Taiwan University Hospital Beihu BranchTaipei, TaiwanTaking people

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Trial details

Who runs it
National Taiwan University Hospital
Trial code
NCT06968871
Record updated
30 October 2026
Original description
The Pap test plays a crucial role in the early detection of cervical cancer. A pilot single-center randomized controlled trial applied the peak-end concept and added a non-painful step at the end of Pap smear screening, aimed to reduce recalled pain. However, there is still no multicenter study investigating the effect of the modified Pap test on cervical cancer screening participation.Read full original descriptionShow less

Effects of the Ameliorated Pap Test on Cervical Cancer Screening Participation: a Multicenter Randomized Controlled Trial

The Pap test plays a crucial role in the early detection of cervical cancer. A pilot single-center randomized controlled trial applied the peak-end concept and added a non-painful step at the end of Pap smear screening, aimed to reduce recalled pain. However, there is still no multicenter study investigating the effect of the modified Pap test on cervical cancer screening participation.

The present project is the first multicenter randomized controlled trial to expand the current scope of the peak-end theory into Pap tests and cervical cancer screening participation by adding a non-painful step at the end of Pap smear screening. Our multidisciplinary team (NTUH Pap Study Group) aims to provide innovative, feasible, and low-cost strategies for cervical cancer screening participation.

Inclusion: Women aged 25 or above.

Exclusion: Any active cancer at study entry (defined as cancer diagnosed or treated within the previous 6 months, recurrent, regionally advanced or metastatic cancer); Previous hysterectomy, pelvic surgery, or radiotherapy; Active vaginal or uterus infection; Ongoing menstruation; Pregnancy; Incapability of understanding the numeric pain scales; Analgesic use within 24 hours.

ClinicalTrials.gov NCT06968871