Synbiotic supplement tested in newborns exposed to antibiotics at birth
Tests whether a synbiotic supplement changes gut bacteria in newborns given antibiotics at birth.
Plain-language title generated from the registry record
Registry title: Resilience to Antibiotic-induced Obesogenic Microbiota: Discovering Mechanism of Microbiota Modulation
Key facts
- Where
- Turku, FinlandSee the site
Where in Finland
- Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of TurkuTurku, FinlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Turku University Hospital
- Trial code
- NCT06974994
- Record updated
- 16 May 2025
- Original description
The aim is to study whether the microbiota of children who are exposed to antibiotics at birth could be modified by synbiotic supplement and thereby reduce the risk of obesity, chronic diseases and respiratory tract infections. A total of 125 mother-child pairs will be recruited in this randomized, double-blind, placebo-controlled study. Infants are randomized to receive either a synbiotic supplement or a placebo for 2 months, after which their growth and morbidity will be monitored at the research clinic for 2 years.Read full original descriptionShow less
Resilience to Antibiotic-induced Obesogenic Microbiota Vertically Transferred to the Neonatal Gut: Discovering Mechanism of Microbiota Modulation
The aim is to study whether the microbiota of children who are exposed to antibiotics at birth could be modified by synbiotic supplement and thereby reduce the risk of obesity, chronic diseases and respiratory tract infections. A total of 125 mother-child pairs will be recruited in this randomized, double-blind, placebo-controlled study. Infants are randomized to receive either a synbiotic supplement or a placebo for 2 months, after which their growth and morbidity will be monitored at the research clinic for 2 years.
Inclusion: Pregnant women (n=125) and their newborn children who receive antibiotic treatment at delivery.
Exclusion: Suspected malformation or serious condition of the foetus and neonates; Serious infection or other conditions not permitting breast milk feeding; Chorioamnionitis; Pre-eclampsia and hepatogestosis.