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Studies how social feedback affects brain activity in people with epilepsy

Tests how social feedback affects brain recordings in adults with epilepsy.

Plain-language title generated from the registry record
Registry title: Effects of Social Feedback on Intracranial EEG

Key facts

Where
Lebanon, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Source: NCT06975800, who can take part

Where in United States

  • Dartmouth Hitchcock Medical CenterLebanon, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Trustees of Dartmouth College
Trial code
NCT06975800
Record updated
1 July 2026
Original description
This study aims to assess the impact of social influence on direct neural recordings in human patients undergoing surgical treatment of epilepsy. 24 patients recruited from the Epilepsy Center at Dartmouth Health Medical Center (DHMC) will undergo electrode implantation throughout the brain to localize epileptogenic zones. Patients will be asked to rate their provider's warmth, competence, and other, similar traits associated with care-competency. They will then complete the picture-induced fear and math portions of the multimodal negative affect task (MNAT) during which iEEG is recorded.Read full original descriptionShow less

Effects of Social Feedback on Intracranial EEG

This study aims to assess the impact of social influence on direct neural recordings in human patients undergoing surgical treatment of epilepsy. 24 patients recruited from the Epilepsy Center at Dartmouth Health Medical Center (DHMC) will undergo electrode implantation throughout the brain to localize epileptogenic zones. Patients will be asked to rate their provider's warmth, competence, and other, similar traits associated with care-competency. They will then complete the picture-induced fear and math portions of the multimodal negative affect task (MNAT) during which iEEG is recorded.

Inclusion: Patients must be between 18-65 years of age; Patients must have a diagnosis of refractory epilepsy undergoing intracranial EEG recording for clinical purposes; Patients with a legal guardian will be considered for participation if they are interested and, in the judgment of the research team, they are capable of performing the cognitive tasks required of the study. In those instances, the patient and their legal guardian will both participate in the informed consent process, with the legal guardian signing the consent form.

Exclusion: Patient has additional neurological condition (such as stroke or dementia) or a psychiatric condition (such as active psychosis or suicidal ideation) and are deemed inappropriate for the study; Patients are not able to provide informed consent for any reason (e.g. encephalopathic, experiencing a seizure).

ClinicalTrials.gov NCT06975800