Tests a cannula during eye surgery for glaucoma and cataract
Compares a cannula with extra irrigation in adults with pseudoexfoliative glaucoma and cataract.
Plain-language title generated from the registry record
Registry title: Efficacy and Safety of Tran Cannula in Combined Pseudoexfoliative Glaucoma and Cataract Surgery Compared With Augmented Ocular Irrigation
Key facts
- Where
- Avranches, Paris, and St-Malo, FranceSee the 3 sites
Where in France
- Hôpital Privé de la BaieAvranches, FranceTaking people
- Fondation RothschildParis, FranceNo longer taking part
- Clinique de la Côte d'EmeraudeSt-Malo, FranceNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hôpital Privé de la Baie
- Trial code
- NCT06979752
- Record updated
- 30 September 2026
- Original description
Pseudoexfoliative glaucoma is a glaucoma secondary to pseudoexfoliative syndrome; cataract surgery is often more difficult, with more complications. Tran's cannula is a single-use irrigation system designed for cleaning, with the pseudoexfoliative material remaining in the trabecular meshwork.Read full original descriptionShow less
Efficacy and Safety of Tran Cannula in Combined Pseudoexfoliative Glaucoma and Cataract Surgery Compared With Augmented Ocular Irrigation
Pseudoexfoliative glaucoma is a glaucoma secondary to pseudoexfoliative syndrome; cataract surgery is often more difficult, with more complications. Tran's cannula is a single-use irrigation system designed for cleaning, with the pseudoexfoliative material remaining in the trabecular meshwork.
The main objective of this study is to evaluate the efficacy of the Tran cannula, in comparison with increased irrigation, in lowering intraocular pressure (IOP) in patients with pseudoexfoliative glaucoma and treated for glaucoma, and with an indication for isolated cataract surgery.
Inclusion: Patients with cataract and early-to-moderate pseudoexfoliative glaucoma (GPX) scheduled for isolated cataract surgery; Reliable visual field, Humphrey 24-2, Sita-Fast, with typical glaucoma alterations, and with mean deviation ≤-12 dB; OCT with ganglion cell alterations and fibers typical of glaucoma; Typical glaucomatous neuropathy; Slit-lamp signs of pseudoexfoliation; Open angle (2 to 4, according to Shaffer classification) determined by gonioscopy; Untreated eye pressure >21 mmHg and <33 mmHg.
Exclusion: History of laser trabeculoplasty (TLA or SLT) in the previous 12 months; History of intraocular surgery in the last 12 months, history of trauma; Pachymetry < 490 μm or > 620 μm; or corneal pathology or other condition that makes accurate IOP measurements with flattening tonometry, ultrasonic pachymetry or specular microscopy impossible; Visual acuity below "finger count; Presence of other ophthalmological pathologies (except cataract or mild dry eye); Myopia ≥ 6 dioptres, hyperopia ≥ 5 dioptres; Iridocorneal angle closure (and angle-closure glaucoma), any other type of non-pseudoexfoliative glaucoma, iris neovascularization; Presence of severe systemic pathologies.