Using breath and blood tests to prioritize asthma testing in children and adults
Studies breath and blood tests to help prioritize asthma testing in people with suspected asthma.
Plain-language title generated from the registry record
Registry title: PROPULSION SANTE: Inflammometry to Improve the Diagnostic Trajectory in Situations of Suspected Asthma in Children and Adults
Key facts
- Where
- Montreal and Sherbrooke, CanadaSee the 3 sites
Where in Canada
- CHU Sainte-JustineMontreal, CanadaNot yet recruiting
- Montreal Children's HospitalMontreal, CanadaNot yet recruiting
- CIUSSS de l'Estrie-CHUSSherbrooke, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Université de Sherbrooke
- Trial code
- NCT06981169
- Record updated
- 30 April 2026
- Original description
The objective of this observational study is to assess the relevance of inflammometry (based on the measurement of fractional exhaled nitric oxide (FeNO) and blood eosinophil count (BEC)) as a tool for prioritizing respiratory diagnostic tests.Read full original descriptionShow less
PROPULSION SANTE: Inflammometry to Improve the Diagnostic Trajectory in Situations of Suspected Asthma in Children and Adults
The objective of this observational study is to assess the relevance of inflammometry (based on the measurement of fractional exhaled nitric oxide (FeNO) and blood eosinophil count (BEC)) as a tool for prioritizing respiratory diagnostic tests.
The study will evaluate the role of inflammometry (FeNO and BEC) in prioritizing diagnostic respiratory tests. It will include patients aged six and older with suspected asthma, referred by non-pulmonologists for diagnostic asthma testing (spirometry or methacholine challenge test) at three hospital centers: Sherbrooke University Hospital Center (CHUS), Sainte-Justine University Hospital Center (CHU Sainte-Justine), and the Montreal Children's Hospital.
The hypothesis is that using inflammometry as a prioritization tool would reduce diagnostic delays for high-risk patients with elevated biomarkers. This study could help shorten wait times, relieve congestion in diagnostic testing queues, and improve the diagnostic pathway. Additionally, it would enhance the interpretation of pulmonary function test results by incorporating inflammometry findings, leading to better patient stratification.
Patients referred from primary care will undergo pulmonary function testing (spirometry ± methacholine challenge) and, as part of the study:
FeNO measurement using a portable device Blood test for eosinophil count Questionnaire on asthma control and quality of life, completed at the visit and at follow-ups at 4, 8, and 12 months
Inclusion: patients age 6 and older; referred by primary care ofr an asthma diagnostic test (spirometry or methacholine challenge).
Exclusion: referred by pulmonologist.