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Taking people in United StatesNo phase

Cannabis Association With Sleep Study

Key facts

Who runs it
Oregon Health and Science University
Where
Portland, United StatesSee the site
Trial code
Status
Recruiting
People taking part
60 people, planned
Started
1 Mar 2026
Expected to end
30 Jun 2032
Type of study
Interventional, 2 groups
Treatments tested
  • Manipulation of Sleep Duration
Record updated
19 October 2026

Who can take part

Age
21 years to 29 years
Sex
Women and men
Healthy volunteers
Can take part

The registry criteria, word for word

Show all 21 criteriaShow less

Who can take part

  • fluent in English
  • 18.5<BMI<40 kg/m2
  • no shift work in the last 12 months
  • no travel across time zones in the last 2 months

Who cannot take part

  • Chronic disease-Medical history/prior diagnosis of the following:
  • Drug/Alcohol use criteria:
  • Illicit drugs apart from cannabis or related products are prohibitive
  • Use of prescription or over-the-counter medications or supplements that affect sleep are also exclusionary
  • Prior Shift Work:
  • Volunteers must have no history of working irregular day and night hours, regular night work, or rotating shift work for the 3 months prior to the study
  • cardiometabolic disease (e.g., myocardial infarction, angina, diabetes)
  • essential hypertension
  • hepatic impairment
  • restless legs syndrome
  • neurological disease (e.g., early onset dementia)
  • unstable psychiatric disorders (e.g., bipolar disorder, schizophrenia, major depression with suicidality)
  • Participants who consume >14 alcoholic drinks/week and/or have a diagnosis (or history) of alcohol use disorder will be excluded (a toxicological urine screen will be conducted to verify reported non-use during the initial screening and on the day of admission to the in-laboratory portion of the study)
  • severe obstructive sleep apnea
  • parasomnia
  • Volunteers may consume caffeine, however, >3 cups of coffee (or otherwise equivalent of >300mg/day) is prohibitive
  • Contraceptives are required for women and will continue to be taken throughout the experiment

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 21 and 29 years old?

Where in United States

  • OHSUPortland, United StatesContact: Nicole Bowles, PhDTaking people

About the trial

What the trial wants to find out

The purpose of this study is to learn more about cannabis use, sleep, and stress, and whether there is any relationship between the three.

The 2 groups in the trial

  • Sleep RestrictionTreatment being tested

    After a baseline assessment of sleep, participants in this arm will undergo 2 nights of restricted sleep (4 hour time in bed).

    Treatment: Manipulation of Sleep Duration

  • Sleep ExtensionTreatment being tested

    After a baseline assessment of sleep, participants in this arm will undergo 3 nights of an extended sleep opportunity (10 hour time in bed).

    Treatment: Manipulation of Sleep Duration

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Longitudinal Reciprocal Relationships Between Cannabis Use, Sleep, and the HPA-axis (CaSS)
Fit questions
Built from NCT06982950, who can take part
Record updated
19 October 2026