Frontlight ResearchEarly access
Taking people in United StatesNo phase
Cannabis Association With Sleep Study
Key facts
- Who runs it
- Oregon Health and Science University
- Where
- Portland, United StatesSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 60 people, planned
- Started
- 1 Mar 2026
- Expected to end
- 30 Jun 2032
- Type of study
- Interventional, 2 groups
- Treatments tested
- Manipulation of Sleep Duration
- Record updated
- 19 October 2026
Who can take part
- Age
- 21 years to 29 years
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 21 criteriaShow less
Who can take part
- fluent in English
- 18.5<BMI<40 kg/m2
- no shift work in the last 12 months
- no travel across time zones in the last 2 months
Who cannot take part
- Chronic disease-Medical history/prior diagnosis of the following:
- Drug/Alcohol use criteria:
- Illicit drugs apart from cannabis or related products are prohibitive
- Use of prescription or over-the-counter medications or supplements that affect sleep are also exclusionary
- Prior Shift Work:
- Volunteers must have no history of working irregular day and night hours, regular night work, or rotating shift work for the 3 months prior to the study
- cardiometabolic disease (e.g., myocardial infarction, angina, diabetes)
- essential hypertension
- hepatic impairment
- restless legs syndrome
- neurological disease (e.g., early onset dementia)
- unstable psychiatric disorders (e.g., bipolar disorder, schizophrenia, major depression with suicidality)
- Participants who consume >14 alcoholic drinks/week and/or have a diagnosis (or history) of alcohol use disorder will be excluded (a toxicological urine screen will be conducted to verify reported non-use during the initial screening and on the day of admission to the in-laboratory portion of the study)
- severe obstructive sleep apnea
- parasomnia
- Volunteers may consume caffeine, however, >3 cups of coffee (or otherwise equivalent of >300mg/day) is prohibitive
- Contraceptives are required for women and will continue to be taken throughout the experiment
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 29 years old?
Where in United States
- OHSUPortland, United StatesContact: Nicole Bowles, PhDTaking people
About the trial
What the trial wants to find out
The purpose of this study is to learn more about cannabis use, sleep, and stress, and whether there is any relationship between the three.
The 2 groups in the trial
- Sleep RestrictionTreatment being tested
After a baseline assessment of sleep, participants in this arm will undergo 2 nights of restricted sleep (4 hour time in bed).
Treatment: Manipulation of Sleep Duration
- Sleep ExtensionTreatment being tested
After a baseline assessment of sleep, participants in this arm will undergo 3 nights of an extended sleep opportunity (10 hour time in bed).
Treatment: Manipulation of Sleep Duration
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Longitudinal Reciprocal Relationships Between Cannabis Use, Sleep, and the HPA-axis (CaSS)
- Fit questions
- Built from NCT06982950, who can take part
- Record updated
- 19 October 2026