Comparing Stool Blood Test and Colonoscopy for Checking Bowel Health After Polyp Removal
Tests a stool blood test against colonoscopy to monitor colon cancer risk after polyp removal.
Plain-language title generated from the registry record
Registry title: Randomized Trial Comparing Fecal Testing (FIT) to Colonoscopy for Post-polypectomy Surveillance
Key facts
- Where
- Arendal, NorwaySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 75 years old?
Source: NCT06983639, who can take part
Where in Norway
- Sørlandet sykehus HFArendal, NorwayTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sorlandet Hospital HF
- Trial code
- NCT06983639
- Record updated
- 15 January 2026
- Original description
From observational studies, it is know that the risk of developing colorectal cancer after polyp removal is lower if the patients adheres to surveillance recommendations. However, colonoscopy is burdensome for patients and colonoscopy availability is limited in many parts of the world. In addition, more than half of surveillance colonoscopies are without any findings. The trial investigates whether surveillance using fecal testing for blod is as good as colonoscopy after removal of colorectal polyps.Read full original descriptionShow less
FIT Versus Colonoscopy for Post-polypectomy Surveillance
From observational studies, it is know that the risk of developing colorectal cancer after polyp removal is lower if the patients adheres to surveillance recommendations. However, colonoscopy is burdensome for patients and colonoscopy availability is limited in many parts of the world. In addition, more than half of surveillance colonoscopies are without any findings. The trial investigates whether surveillance using fecal testing for blod is as good as colonoscopy after removal of colorectal polyps.
Inclusion: High-quality baseline colonoscopy with adequat cleansing and cecal intubation; Remocval of at least one advanced adenoma; Clean colon (all polyps removed); Signed informed consent.
Exclusion: Colorectal cancer; History of surgical colon resection for any reason; Genetic cancer syndrome (adenomatous or serrated polyposis syndrome; Lynch or Lynch-like syndrome); History of advanced serrated lesion, defined as SSL≥ 10mm or with dysplasia; Inflammatory bowel disease; ≥ 10 adenomas at baseline colonoscopy (cumulative); On-going palliative care for any reason.