NCT06984822Recruiting
Evaluation of Serum- and OCT Biomarkers in Patients With DME Treated With Anti-VEGF or Dexamethasone Implant
Evaluation of Serum and Ocular Coherence Tomography Biomarkers in Patients With Diabetic Macular Edema Treated With Anti-VEGF or Dexamethasone Implant
Source: ClinicalTrials.gov · Last updated 21 Nov 2025
Brief summary (registry, in English)
This study aims to investigate the association between serum biomarkers and clinical response to anti-VEGF or dexamethasone implant by assessing OCT-biomarkers in patients with diabetic macular edema, DME, and to compare these with a group of naive patients (those not previously treated for DME).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 5 May 2025
- Start date
- 1 Aug 2025
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Vastra Gotaland Region
- Diseases
- Diabetic eye disease
- NCT number
- NCT06984822
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 1 Aug 2025 to the primary completion date, 31 Dec 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior history of any other macular disease.
- Previous treatment with dexamethasone implants in the last six months for those in the anti-VEGF group.
- Previous treatment with anti-VEGF in the last two months for those in the dexamethasone implant group.
- Prior vitreoretinal surgery.
- Previous laser treatment of the macula.
- Previous panretinal photocoagulation.
- Ocular surgery in the previous 3 months.
Who the study is looking for
- Type I or type II DM.
- DME involving the center of the fovea with CFT more than 280 microns and the presence of intraretinal cysts.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ögonmottagning Mölndal/SU Coordinator of this site? Confirm its status | Mölndal | Sweden | Not yet recruiting |
| Sahlgrenska University Hospital, Department of Ophthalmology Coordinator of this site? Confirm its status | Mölndal | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.