Tests Local Anesthesia During Prostate Biopsy Under Sedation
Tests numbing medicine during a prostate biopsy in men with prostate cancer.
Plain-language title generated from the registry record
Registry title: A Study of Changes to Prostate Procedures
Key facts
- Where
- Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, and Uniondale, United StatesSee the 7 sites
- Phase
- Phase 3
Where in United States
- Memorial Sloan Kettering Cancer Center at Basking Ridge (Consent Only)Basking Ridge, United StatesTaking people
- Memorial Sloan Kettering Suffolk - Commack (Consent Only)Commack, United StatesTaking people
- Memorial Sloan Kettering Westchester (Consent only)Harrison, United StatesTaking people
- Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, United StatesTaking people
- Memorial Sloan Kettering Bergen (Consent Only)Montvale, United StatesTaking people
- Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, United StatesTaking people
- Memorial Sloan Kettering Nassau (Consent Only)Uniondale, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Memorial Sloan Kettering Cancer Center
- Trial code
- NCT06986083
- Record updated
- 5 November 2026
- Original description
The purpose of this study is to look whether using local anesthesia during a transperineal prostate biopsy, while put to sleep by IV sedation, helps reduce the number of people who feel significant pain in the recovery room. The researchers will also look at how local anesthesia affects the amount of pain medication used, how quickly people can go home after the biopsy, and how well they recover after leaving the hospital.Read full original descriptionShow less
A Randomized Controlled Trial of Modifications to Prostate Needle-Based Procedures
The purpose of this study is to look whether using local anesthesia during a transperineal prostate biopsy, while put to sleep by IV sedation, helps reduce the number of people who feel significant pain in the recovery room. The researchers will also look at how local anesthesia affects the amount of pain medication used, how quickly people can go home after the biopsy, and how well they recover after leaving the hospital.
Inclusion: Local anesthesia versus no local anesthesia during transperineal biopsy, while the patient is under IV sedation:; Patients scheduled for transperineal prostate biopsy at the JRSC or Monmouth; Standardization of a periprocedural pathway versus usual care for focal gland ablation:; Patients scheduled for a partial prostate gland ablation procedure at the JRSC.
Exclusion: Local anesthesia versus no local anesthesia during transperineal biopsy, while patient is under IV sedation:; None; Standardization of a periprocedural pathway versus usual care for focal gland ablation:; None.