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NCT06987058Enrolling by invitationPhase 2

RVU120 Rollover Study

An Open-label Multicenter Rollover Study to Provide Continued Treatment to Participants Previously Enrolled in a RVU120 Clinical Study

Source: ClinicalTrials.gov · Last updated 17 Sept 2026

Brief summary (registry, in English)

This is a multicenter rollover study to provide continued treatment to eligible participants previously enrolled in a RVU120 clinical study and to evaluate the safety of the treatment and record the time on treatment when continued under the same regimen as in the parent study. To be eligible for this rollover study, participants must be continuing to benefit from their treatment, show an acceptable safety profile, and not have access to commercially available comparator anticancer therapy. Once transitioned to this study, participants will continue with their next planned dose per the regimen of their parent study.

Status (registry)
Enrolling by invitation
Phase (registry)
Phase 2
Study type
Interventional
Enrollment
14 (estimated)
First submitted
15 May 2025
Start date
4 Dec 2025
Primary completion date
Dec 2026
Lead sponsor
Ryvu Therapeutics SA
NCT number
NCT06987058
EU CT number
2025-521673-14-00

What you commit to

  • Study type: Interventional · Phase 2
  • Planned participants: 14
  • From 4 Dec 2025 to the primary completion date, Dec 2026
  • 10 sites in 4 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Concurrent participation in any therapeutic clinical study other than the parent study.

Other

  • Presence of toxicity that cannot be adequately managed.

Who the study is looking for

  • The participant is enrolled in a RVU120 clinical study and receiving RVU120-based treatment given alone or in combination for at least 5 cycles.
  • The participant is currently benefiting from, and expected to continue to benefit from, RVU120-based treatment according to the criteria set out in the parent study protocol and according to the judgment of the investigator and sponsor.
  • The participant does not have access to commercially available comparator anticancer therapy.
  • Contraceptive use by participants or participant partners should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies.
  • The participant signed the rollover study ICF prior to any study-related procedure or study data collection.
  • The participant agrees not to donate blood during study participation and until 28 weeks (\~6.5 months) after the last dose.
  • The investigator considers the participant to be eligible for participation in the rollover study.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (10)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Clínica Universidad de navarra
Coordinator of this site? Confirm its status
PamplonaSpainNot yet recruiting
Centre Hospitalier Universitaire de Nice
Coordinator of this site? Confirm its status
NiceFranceRecruiting
Centre Hospitalier Universitaire de Bordeaux
Coordinator of this site? Confirm its status
PessacFranceRecruiting
University Hospital Consorziale Policlinico
Coordinator of this site? Confirm its status
BariItalyNot yet recruiting
M2M Med. Sp. z o.o. Sp. j.
Coordinator of this site? Confirm its status
ChorzowPolandRecruiting
Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki W Krakowie
Coordinator of this site? Confirm its status
CracowPolandRecruiting
Uniwersyteckie Centrum Kliniczne
Coordinator of this site? Confirm its status
GdanskPolandRecruiting
Pratia Hematologia Sp. Z o. o
Coordinator of this site? Confirm its status
KatowicePolandRecruiting
Uniwersytecki Szpital Kliniczny Nr 1 w Lublinie
Coordinator of this site? Confirm its status
LublinPolandRecruiting
Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu
Coordinator of this site? Confirm its status
WroclawPolandRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.