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Studies how minor stroke patients may recover quality of life over time

Tests whether early patient details can predict quality of life after a minor ischemic stroke.

Plain-language title generated from the registry record
Registry title: BREMISS : Brain Resilience Minor Stroke Study

Key facts

Where
Brest, FranceSee the site

Where in France

  • CHU de BrestBrest, FranceTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University Hospital, Brest
Trial code
NCT06995040
Record updated
23 February 2026
Original description
The objective of this clinical trial is to develop, based on patients' initial characteristics (in the first few weeks following the stroke), a predictive model of quality of life more than 4 years after the stroke in patients who have suffered a minor ischemic stroke.Read full original descriptionShow less

Initial Predictors of Long-term Brain Resilience After Minor Ischemic Stroke: a Study Nested in the Brest Stroke Population-based Registry

The objective of this clinical trial is to develop, based on patients' initial characteristics (in the first few weeks following the stroke), a predictive model of quality of life more than 4 years after the stroke in patients who have suffered a minor ischemic stroke.

The main question it aims to answer is:

- Is it possible to predict the quality of life of patients who have suffered a minor ischemic stroke based on their initial characteristics?

To do this, retrospective and prospective data collected as part of the study will be analyzed using a conventional statistical approach and algorithms based on AI approaches in order to create a predictive model.

Participants will be asked to:

* Complete questionnaires * Provide a saliva sample (optional) * Undergo an MRI scan (optional)

Inclusion: Cases of stroke in the Brest Stroke Registry (BSR); Ability to sign informed consent; Patients followed-up > 4 years during the study period; NIHSS score ≤ 5 on admission; First stroke above 18 and before 75-year old; Rankin before stroke < 1; Possibility to draw saliva samples for genomic study; Possibility to perform Cerebral MRI.

Exclusion: Patients with transient neurological deficits resolving within one hour and normal brain imaging will be excluded; Not affiliated to social security; Patient under legal protection or deprived of liberty by a judicial or administrative decision; Patient unable to sign informed consent; Patient whose follow-up will be impossible.

ClinicalTrials.gov NCT06995040