Frontlight ResearchEarly access
Enrolling by invitationNo phase
SMART-CPT for PTSD/Concussion Implementation
Key facts
- Who runs it
- San Diego Veterans Healthcare System
- Where
- San Diego, United StatesSee the site
- Trial code
- Status
- Enrolling by invitation
- People taking part
- 124 people, planned
- Started
- 1 Dec 2024
- Expected to end
- Jun 2027
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- SMART-CPT
- CPT
- Record updated
- 4 June 2025
Who can take part
- Age
- 18 years to 55 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 17 criteriaShow less
Who can take part
- PTSD diagnosis
- mild TBI sustained greater than three months prior to enrollment
- cognitive complaints
- not medicated or stable on prescribed psychiatric medication for at least 6 weeks prior to study enrollment with no anticipated/pending medication changes
- English literacy
Who cannot take part
- mTBI sustained less than 3 months previously
- suicidal intent or attempt within the previous month
- prior completion of five or more sessions of CPT or cognitive rehabilitation; -concurrent participation in other intervention studies for PTSD or TBI
- history of moderate, severe, or penetrating TBI
- history of other significant neurological condition unrelated to TBI
- severe psychiatric disturbance expected to interfere with successful completion of the study
- current severe alcohol or other substance use disorder
- life threatening or unstable medical illness
- dementia
- current homicidal ideation
- impaired decision making capacity
- inability to read
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 55 years old?
Where in United States
- VA San DiegoSan Diego, United StatesEnrolling by invitation
About the trial
What the trial wants to find out
The clinical implementation trial will evaluate effectiveness and feasibility, acceptability, appropriateness, barriers, and facilitators of implementing SMART-CPT, a treatment targeting the two primary factors leading to poor outcomes following concussion, in Veterans. It will test effectiveness and broad implementation feasibility of SMART-CPT compared to standard Cognitive Processing Therapy (CPT).
The 2 groups in the trial
- SMART-CPTTreatment being tested
- CPTExisting treatment, for comparison
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- SMART-CPT for PTSD and History of Concussion: A Pragmatic Implementation Trial
- Fit questions
- Built from NCT06995612, who can take part
- Record updated
- 4 June 2025