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Virtual Reality Training for Neglect After Stroke

Tests a virtual reality program for attention loss on one side in adults after stroke.

Key facts

Who runs it
Universiteit Antwerpen
Where
Antwerp, BelgiumSee the site
Trial code
Registry title
Assessment and Treat Neglect Patients With a VR Application
Status
Not yet recruiting
People taking part
30 people, planned
Started
1 Jun 2025
Expected to end
1 Jul 2027
Type of study
Interventional, 3 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Virtual reality training
  • physiotherapy and occupational therapy
  • Assessment
Record updated
31 May 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who have had a stroke in one side of the brain. It tests a virtual reality program for neglect, where a person overlooks one side of space.

Age
18 years or older
Sex
All sexes can join.
Disease stage
Has had a hemispheric stroke (a stroke in one half of the brain).

Main reasons for not taking part

  • Severe psychiatric disorder, for example psychotic symptoms
  • Neurodegenerative disease before the stroke, for example Alzheimer's or vascular dementia
  • Severe problems understanding written language
  • Medical implant, such as a cochlear implant or a pacemaker
  • Severe vision problem that glasses cannot correct during training

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • Age 18 years or older
  • Able to provide informed consent
  • have had a hemispheric stroke

Who cannot take part

  • Have a medical implant, such as a cochlear implant or a pacemaker
  • Have a severe comorbid psychiatric (E.g. psychotic symptoms) disorder
  • Have a premorbid neurodegenerative disease (E.g. Alzheimer's dementia, vascular dementia)
  • Have a severe visual impairment that cannot be corrected by wearing glasses while training
  • Have a history of epileptic seizures The following exclusion criteria do not apply to the Non-VSN stroke group
  • Have severe written language comprehension deficits
  • Do not show signs of a spatial asymmetry in performance on a battery of screening tasks
  • Having visual field deficits or lesions in the occipital lobe

Where in Belgium

  • Rehabilitation Sciences and Physiotherapy, Faculty of Medicine and Health Sciences, University of AntwerpAntwerp, BelgiumContact: MENGDI LUNo longer taking part

About the trial

What the trial wants to find out

The objective of this project is to investigate the effectiveness of neglect training in our self-developed VR application "SpatialSense". The investigators aim to reach the following goals:

Read full original descriptionShow less

i. Compare conventional neglect therapy for neglect training with SpatialSense to evaluate the impacts on neglect recovery to see whether the VR therapy improves the clinical outcomes, such as balance recovery, perception of verticality, quality of life, independence in daily activities, and cognitive impairment, after rehabilitation training.

ii. Analyze and compare the search strategies employed by stroke patients with VSN and those without VSN during the execution of the search task with SpatialSense to summarize typical visual scanning strategies for facilitation, rehabilitation training, and improving the transfer effect in daily activities.

The experimental group will receive both conventional OT and PT treatment, but 3 days a week, half an hour of conventional treatment will be replaced by treatment with SpatialSense software. The control group will receive their regular dose-matched conventional OT and PT sessions without interference. The experimental group will receive SpatialSense training 3 times a week for a consecutive 4 weeks (12 sessions in total of 30 minutes).

The 3 groups in the trial

  • VR groupTreatment being tested

    The experimental group will receive both conventional OT and PT treatment but 3 days a week, half an hour of conventional treatment will be replaced by treatment with SpatialSense software. The experimental group will receive SpatialSense training 3 times a week for a consecutive 4 weeks (12 sessions in total of 30 minutes).

    Treatment: Virtual reality training, physiotherapy and occupational therapy, and Assessment

  • ConventionalExisting treatment, for comparison

    The control group will have the assessment on SpatialSense and then receive their regular dose-matched conventional OT and PT sessions without interference. All people with stroke receive conventional occupational (OT) and physical therapy (PT) for 1 hour each. In a total of 4 weeks, 5 times a week.

    Treatment: physiotherapy and occupational therapy and Assessment

  • Non-neglect stroke groupOther group

    Prior to the assessment in SpatialSense, the screen of the head-mounted display will be projected onto a laptop and the eye tracking will be calibrated to the participants' eye positions by the investigator. Then, all participants will perform the assessment part in SpatialSense. During assessments with SpatialSense, participants will sit in a wheelchair or on a straight-back chair. The trunk will be restricted to the chair. Finally, the data will be exported from SpatialSense and analyzed by investigators to define different search strategies while performing scanning tasks.

    Treatment: Assessment

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Assess and Treat Visuospatial Neglect in Central Neurological Conditions Via an Innovative Virtual Reality Software
Plain-language title
Virtual Reality Training for Neglect After StrokeGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
31 May 2025