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Surgical technique for removing the uterus in cervical cancer while sparing nerves

Studies a different nerve-sparing surgery for cervical cancer in adults 18 years or older.

Plain-language title generated from the registry record
Registry title: Revisiting the Concept of Nerve Sparing Radical Hysterectomy

Key facts

Where
Milan, ItalySee the site

Where in Italy

  • Fondazione IRCCS Istituto Nazionale dei Tumori di MilanoMilan, ItalyNo longer taking part

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Trial details

Who runs it
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Trial code
NCT06999824
Record updated
31 May 2025
Original description
Nerve-sparing radical hysterectomy aims to preserve the autonomic innervation of pelvic organs. In most studies, the preservation of the parasympathetic component of pelvic innervation is achieved by sparing the lymphovascular-neural tissue located at the base of the lateral paracervical tissue. This study explores an alternative surgical technique based on a different anatomical pathway of parasympathetic fibers, running more cranially and deeply within the pararectal space.Read full original descriptionShow less

Revisiting the Concept of Nerve Sparing Radical Hysterectomy

Nerve-sparing radical hysterectomy aims to preserve the autonomic innervation of pelvic organs. In most studies, the preservation of the parasympathetic component of pelvic innervation is achieved by sparing the lymphovascular-neural tissue located at the base of the lateral paracervical tissue. This study explores an alternative surgical technique based on a different anatomical pathway of parasympathetic fibers, running more cranially and deeply within the pararectal space.

ClinicalTrials.gov NCT06999824