NCT07010250Recruiting
Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis
Source: ClinicalTrials.gov · Last updated 30 Jun 2026
Brief summary (registry, in English)
The project is to explore in humans the hypothesis of the link between the alteration of tubulo-interstitial metabolism and the rate of deterioration of renal function by comparing various nephropathies.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 146 (estimated)
- First submitted
- 5 May 2025
- Start date
- 3 Nov 2025
- Primary completion date
- 2 Nov 2029
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- NCT number
- NCT07010250
What you commit to
- Study type: Observational
- Planned participants: 146
- From 3 Nov 2025 to the primary completion date, 2 Nov 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Kidney transplant patient
Other
- Patient on dialysis (hemodialysis or peritoneal dialysis)
- Patient under legal protection, guardianship or curatorship
- Pregnancy or breastfeeding
- Enrollement in an interventional study except studies relating to ANCA vasculitis and nephropathy with mesangial IgA deposits.
Who the study is looking for
- Patients with an indication for initial diagnostic PBR on native kidney
- 18 ans ≥ Age ≤ 90 ans
- Affiliation to french health insurance
- Patient having given consent
- For the ANCA vasculitis group:
- Diagnosis of ANCA vasculitis retained on renal biopsy with ANCA anti-proteinase 3 (PR3) or ANCA anti-myeloperoxidase (MPO)
- For the control groups:
- Diagnosis retained after the renal biopsy
- Interstitial Nephritis
- Or glomerular nephropathy such as minimal change nephropathy
- Or Segmental hyalinosis in itscollapsing form
- Or Extramembranous Glomerulopathy,
- Or glomerulopathy with mesangial IgA deposits
- Or diabetic nephropathy.
Age in the registry: 18 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Georges-Pompidou European Hospital, AP-HP Coordinator of this site? Confirm its status | Paris | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.