Measuring Body Resilience in People With Parkinson's Disease
Studies body resilience and compares cycling with treadmill walking in people with Parkinson's disease.
Plain-language title generated from the registry record
Registry title: Characterising Physiological Resilience in People With Parkinson's Disease
Key facts
- Where
- Derby, United KingdomSee the site
Where in United Kingdom
- The University of Nottingham/Medical SchoolDerby, United KingdomNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Nottingham
- Trial code
- NCT07013513
- Record updated
- 10 June 2025
- Original description
Parkinson's disease (PD) is a condition that affects movement and gets worse over time. It is more common in older adults. People with PD may have symptoms like shaking, stiff muscles, slow movement, and trouble with balance. They may also experience other issues like pain, depression, anxiety, and memory problems, which can make daily life harder.Read full original descriptionShow less
Characterising the Physiological Resilience of People With Parkinson's Disease - With Feasibility
Parkinson's disease (PD) is a condition that affects movement and gets worse over time. It is more common in older adults. People with PD may have symptoms like shaking, stiff muscles, slow movement, and trouble with balance. They may also experience other issues like pain, depression, anxiety, and memory problems, which can make daily life harder.
Physiological resilience is the body's ability to recover or stay strong despite challenges like aging or illness. People with low resilience may struggle to cope with illness, become less active, and have a higher risk of weakness or hospitalization. Since both PD and low resilience are more common in older adults, understanding how PD affects resilience can help improve care.
This study will look at resilience in people with PD by measuring heart, lung, muscle, coordination, memory, and thinking abilities. It will also compare two types of single-session aerobic exercise-cycling and walking on a treadmill-regarding participants' perspectives. Participants will be randomly chosen to do one of these exercises for 40 minutes at a moderate level. Afterward, they will share their thoughts on how enjoyable and comfortable the exercise was and whether they would continue doing it.
Aerobic exercise is often recommended for people with PD, but it is unclear which type is best for people with PD and which type is mostly preferred by participants with PD. The results of this study will help practitioners make better exercise recommendations for people with PD, leading to better symptom management and a higher quality of life.
Inclusion: Participants who are willing and able to give informed consent for participation in the study; Participants who can walk 30 meters with or without walking aids; Participants who have a confirmed diagnosis of Parkinson's disease by a healthcare professional.
Exclusion: Current or recent (<2 years) malignancy (excluding minor cancers such as skin cancer, or not receiving chemotherapy or radiotherapy within the last 3 months); Cardio- and/or pulmonary diseases except for well-controlled hypertension and asthma; Severe cognitive impairment/dementia; Joint disorders preventing exercise participation.