Studying how nerve sensitivity relates to pain after endometriosis surgery
Follows adults with endometriosis or adenomyosis to see how pain changes after surgery.
Plain-language title generated from the registry record
Registry title: The Influence of Central Sensitization in Endometriosis Disease
Key facts
- Where
- Guangzhou, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for women aged 18-50 with endometriosis or adenomyosis who are having surgery to remove the lesions or the uterus. It studies how central sensitization relates to pain after surgery.
- Age
- 18-50 years
- Sex
- Women only
- Disease stage
- Endometriosis or adenomyosis confirmed by pathology, treated with lesion excision or hysterectomy (with or without removal of both tubes and ovaries).
- Earlier treatment
- Cannot have had a hysterectomy and/or removal of both tubes and ovaries before the baseline.
- Biomarker or test result
- A CSI score or chronic pelvic pain score must be available.
Main reasons for not taking part
- Postmenopausal (natural or after surgery)
- Hysterectomy and/or removal of both tubes and ovaries before baseline
- No CSI or chronic pelvic pain score
- Follow-up after surgery shorter than 6 months
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Source: NCT07014761, who can take part
Where in China
- Sun Yat-sen Memorial Hospital, Sun Yat-sen UniversityGuangzhou, ChinaContact: Yingchen Wu, DoctorNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Trial code
- NCT07014761
- Record updated
- 11 June 2025
- Original description
Endometriosis diseases include endometriosis and adenomyosis. Researchers will include 200 or more patients with endometriosis diseases; collect relevant clinical data such as age, BMI, educational level, history of other diseases, surgical history, smoking and drinking history, pregnancy and childbirth history, pain duration, preoperative CA125 level, hemoglobin, surgical methods (laparotomy / laparoscopy), endometriosis stage, endometriosis location, baseline (preoperative), 1, 3, and 6-month follow-up CSI scores, dysmenorrhea scores, chronic pelvic pain scores, dyspareunia scores, dyschezia scores, back pain scores, to explore the role of central sensitization in postoperative pain of patients with adenomyosis, that is, the relationship between central sensitization and postoperative pain outcomes (chronic pelvic pain, dyspareunia, dyschezia, back pain); evaluate whether the baseline CSI score can predict the severity of postoperative pain; and explore the pain relief of different medications after lesion resection in patients with endometriosis.Read full original descriptionShow less
The Influence of Central Sensitization in Endometriosis Disease
Endometriosis diseases include endometriosis and adenomyosis. Researchers will include 200 or more patients with endometriosis diseases; collect relevant clinical data such as age, BMI, educational level, history of other diseases, surgical history, smoking and drinking history, pregnancy and childbirth history, pain duration, preoperative CA125 level, hemoglobin, surgical methods (laparotomy / laparoscopy), endometriosis stage, endometriosis location, baseline (preoperative), 1, 3, and 6-month follow-up CSI scores, dysmenorrhea scores, chronic pelvic pain scores, dyspareunia scores, dyschezia scores, back pain scores, to explore the role of central sensitization in postoperative pain of patients with adenomyosis, that is, the relationship between central sensitization and postoperative pain outcomes (chronic pelvic pain, dyspareunia, dyschezia, back pain); evaluate whether the baseline CSI score can predict the severity of postoperative pain; and explore the pain relief of different medications after lesion resection in patients with endometriosis.
Inclusion: Patients admitted to the gynaecological ward of Sun Yat-sen Memorial Hospital from March 2025 to March 2027; Age 18-50 years old; Endometriosis focus excision or hysterectomy (with or without bilateral salpingo-oophorectomy, with excision of any complicated lesion); The pathology was adenomyosis or endometriosis.
Exclusion: Postmenopausal (spontaneous or surgical); Hysterectomy and/or bilateral salpingo-oophorectomy (before baseline); Lack of CSI or CPP score; The postoperative follow-up time was less than 6 months.