Post-Implantation Syndrome and Laboratory Markers Following EVAR and TEVAR
Key facts
- Who runs it
- Ataturk University
- Where
- Türkiye1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 300 people enrolled
- Started
- 1 Jan 2018
- Ended
- 15 Apr 2025
- Type of study
- Observational
- Treatments tested
- Endovascular Aortic Intervention
- Record updated
- 11 June 2025
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Patients aged ≥18 years
- Undergoing elective EVAR or TEVAR for abdominal or thoracic aortic aneurysm
- Ability to provide informed consent
- Availability of baseline and follow-up laboratory data (including IL-6, NLR, CRP, leukocyte count, procalcitonin, etc.)
Who cannot take part
- Current use of immunosuppressive or anti-inflammatory therapy
- Evidence of active infection at the time of procedure
- Known autoimmune or inflammatory disease (e.g., rheumatoid arthritis, lupus)
- Malignancy under active treatment
- End-stage renal or hepatic failure
- Incomplete postoperative laboratory data
- Emergency or ruptured aneurysm repair
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The aim of this observational study is to investigate the relationship between postimplantation syndrome (PIS) and laboratory inflammatory parameters following endovascular aortic repair (EVAR/TEVAR). PIS is a systemic inflammatory response that may occur after EVAR or TEVAR and lacks a standardized clinical definition. This study seeks to determine whether specific laboratory biomarkers-particularly white blood cell count, C-reactive protein (CRP), interleukin levels, and neutrophil-to-lymphocyte ratio (NLR)-can serve as reliable indicators for the diagnosis and assessment of PIS.
The group in the trial
- Post-Implantation Syndrome: Lab Trends after EVAR/TEVAR
This cohort includes patients who underwent endovascular aneurysm repair (EVAR) or thoracic endovascular aortic repair (TEVAR). The study investigates the occurrence of post-implantation syndrome (PIS) and its association with early postoperative laboratory markers, including interleukin-6 (IL-6), neutrophil-to-lymphocyte ratio (NLR), leukocyte count, C-reactive protein (CRP), and procalcitonin levels. No additional pharmacologic or procedural interventions were applied beyond standard perioperative care.
Treatment: Endovascular Aortic Intervention
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Biomarkers Predicting Postimplantation Syndrome After Endovascular Aortic Repair (EVAR) and Thoracic Endovascular Aortic Repair (TEVAR)
- Record updated
- 11 June 2025