Compares an etomidate-propofol mix with propofol alone for anesthesia in older surgery patients
Tests a etomidate-propofol mixture against propofol for anesthesia in older abdominal surgery patients.
Plain-language title generated from the registry record
Registry title: Safety of Etomidate-propofol Mixture vs. Propofol for Total Intravenous Anesthesia in Elderly Patients Undergoing Abdominal Surgery
Key facts
- Where
- Wuhan, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 65 and 80 years old?
Source: NCT07019246, who can take part
Where in China
- Tongji HospitalWuhan, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Tongji Hospital
- Trial code
- NCT07019246
- Record updated
- 17 June 2025
- Original description
The purpose of this study is to access the safety of etomidate - propofol mixture vs propofol for total intravenous anesthesia in elderly patients undergoing abdominal surgery.Read full original descriptionShow less
Safety of Etomidate-propofol Mixture vs. Propofol for Total Intravenous Anesthesia in Elderly Patients Undergoing Abdominal Surgery - A Randomized, Double-blind, Controlled Study
The purpose of this study is to access the safety of etomidate - propofol mixture vs propofol for total intravenous anesthesia in elderly patients undergoing abdominal surgery.
Inclusion: ASA Ⅰ~Ⅲ; BMI was 18-28 kg/m2; For elective abdominal surgery under intravenous general anesthesia; The expected duration of anesthesia was 1 to 4 hours.
Exclusion: Liver surgery, renal surgery, adrenal surgery, day surgery; Septic shock and multiple organ failure diagnosed within 14 days; Stroke or transient ischemic attack within 3 months; Patients with unstable angina pectoris or myocardial infarction within 3 months; Arrhythmia requiring treatment was not treated or treatment did not meet expectations; Resting blood pressure ≥180/110 mmHg (2020 ISH hypertension guideline ≥ grade 3 hypertension); Or systolic blood pressure <90mmHg or mean blood pressure <65mmHg; Taking corticosteroids or other immunosuppressants for more than 10 days within 6 months or having a history of adrenal cortex suppression or immune system diseases; Hyperkalemia (serum potassium >5.5mmol/L) within 48 hours; Patients with preoperative diagnosed diabetes mellitus and uncontrolled blood glucose; Diabetic complications were diagnosed before surgery, including diabetic ketoacidosis, hyperosmolar coma, diabetes-related infection, diabetic nephropathy, retinopathy, diabetic cardiomyopathy, diabetic neuropathy, diabetic foot, etc; Severe liver and renal dysfunction.