Pleth Variability Index to Predict Low Blood Pressure During Dialysis
Checks a fingertip pulse measure to predict low blood pressure during regular dialysis.
Plain-language title generated from the registry record
Registry title: Pleth Variability Index for Predicting Low Blood Pressure During Maintenance Hemodialysis
Key facts
- Where
- Wuhu, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults on regular hemodialysis for kidney failure. It studies whether a fingertip measurement can predict low blood pressure during dialysis.
- Age
- 18 to 80 years
- Sex
- Men and women can join.
- Disease stage
- End-stage kidney disease, on maintenance hemodialysis for more than 3 months.
- Earlier treatment
- Must have had regular maintenance hemodialysis for more than 3 months.
Main reasons for not taking part
- Severe heart rhythm problems or significant peripheral vascular disease that could disturb the measurement
- Local swelling, skin lesions or other conditions that prevent accurate measurement
- History of unstable circulation not related to dialysis
- Pregnant or breastfeeding women
- Took part in another interventional study within the past 30 days
This trial only enrols participants on dialysis. The registry sentence this rests on: Diagnosis of end-stage renal disease and undergoing maintenance hemodialysis for more than 3 months.
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07022847, who can take part
Where in China
- The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)Wuhu, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- First Affiliated Hospital of Wannan Medical College
- Trial code
- NCT07022847
- Record updated
- 15 June 2025
- Original description
What is this study about? We are studying whether the Pleth Variability Index (PVI)-a simple, non-invasive measurement from a pulse oximeter-can help predict low blood pressure (hypotension) during routine maintenance hemodialysis. Low blood pressure during dialysis is a common and potentially serious complication. Our goal is to find out if monitoring PVI can help identify patients at risk, so that early action can be taken.Read full original descriptionShow less
The Value of Pleth Variability Index in Predicting Hypotension During Maintenance Hemodialysis: A Prospective Observational Multicenter Study
What is this study about? We are studying whether the Pleth Variability Index (PVI)-a simple, non-invasive measurement from a pulse oximeter-can help predict low blood pressure (hypotension) during routine maintenance hemodialysis. Low blood pressure during dialysis is a common and potentially serious complication. Our goal is to find out if monitoring PVI can help identify patients at risk, so that early action can be taken.
Who can join? Adults aged 18 to 80 years. Patients who have been receiving maintenance hemodialysis regularly for more than 3 months.
Those who are willing and able to participate and sign an informed consent form.
Who cannot join? Patients with severe heart rhythm problems, severe peripheral circulation problems, or swelling that makes PVI measurement unreliable.
Patients who are pregnant or breastfeeding. Patients allergic to the dialysis filter or unable to cooperate with the study procedures.
What will happen during the study? PVI Measurement: Your PVI will be checked with a simple fingertip device before starting dialysis and again 30 minutes after dialysis begins.
Blood Pressure Monitoring: Your blood pressure will be closely watched throughout the dialysis session.
Data Collection: Information about your age, medical history, medications, lab results, dialysis settings, and other standard measurements will be recorded.
What are the benefits and risks? Benefits: By identifying patients at higher risk for low blood pressure during dialysis, the study may lead to safer and more comfortable dialysis treatment in the future.
Risks: All measurements used in this study are safe and non-invasive, with no extra risk compared to routine care.
Your Rights and Safety Participation is completely voluntary-you may leave the study at any time without affecting your medical care.
The study has been reviewed and approved by the hospital's ethics committee. Your privacy and personal data will be strictly protected.
Inclusion: Adults aged 18 to 80 years; Diagnosis of end-stage renal disease and undergoing maintenance hemodialysis for more than 3 months; Able and willing to provide informed consent and comply with study procedures.
Exclusion: Severe cardiac arrhythmias or significant peripheral vascular disease that may interfere with PVI measurements; Local edema, skin lesions, or other conditions that prevent accurate PVI monitoring; History of hemodynamic instability unrelated to dialysis; Known allergy or contraindication to materials used in the hemodialysis circuit; Pregnant or breastfeeding women; Unable to cooperate with study procedures; Participation in another interventional clinical study within the past 30 days.