EoE Food Test Pilot Study
Key facts
- Who runs it
- Children's Hospital of Philadelphia
- Where
- Philadelphia, United StatesSee the site
- Trial code
- Status
- Not yet recruiting
- People taking part
- 50 people, planned
- Starts
- 1 Jan 2027
- Expected to end
- 1 Jan 2029
- Type of study
- Interventional
- Treatments tested
- Assay directed diet change
- Record updated
- 16 March 2026
Who can take part
- Age
- 0 years to 90 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- Diagnosis of Eosinophilic esophagitis (EoE) based on positive esophageal biopsy (>15 eosinophils/high power field) within three months of enrollment
- AND Intention to undergo dietary intervention for treatment of their EoE. AND Unknown contribution of one or more of milk, soy, egg, and wheat to their EoE disease state
- AND Willingness to adopt an elimination diet based in part on the results of the experimental testing
Who cannot take part
- Proton pump inhibitor (PPI)-responsive EoE: Resolution or response of EoE to high-dose PPI (2 mg/kg) alone, at the PI's discretion
- OR Prior medical or surgical history that precludes safely performing an upper endoscopy with biopsy or restriction of diet
- OR Current immunomodulatory therapy >4 weeks (swallowed or systemic steroids, biologic therapy, chemotherapy. etc.) that may interfere with the blood test or biopsy results, at the PI's discretion
- OR Presence of other inflammatory or infectious gastrointestinal pathology (e.g. eosinophilic gastrointestinal diseases, irritable bowel disease, Infectious Colitis, etc.), at the discretion of the Principal Investigator (PI)
- OR Inability to read or understand English
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 0 and 90 years old?
Where in United States
- The Children's Hospital Of PhiladelphiaPhiladelphia, United StatesContact: David A Hill, MD, PhDNot yet recruiting
About the trial
What the trial wants to find out
The objective of this study is to determine the performance characteristics of a series of novel, non-invasive allergen-activated T cell assays designed to identify Eosinophilic esophagitis (EoE) causal foods, when used in conjunction with standard-of-care (SOC) practices.
Read full original descriptionShow less
The question it aims to answer is:
Will assay results accurately predict EoE food allergies in concordance with SOC endoscopies after diet changes?
The group in the trial
- EoE unknownTreatment being tested
Patients with Eosinophilic esophagitis who have not yet identified their disease causal foods and are interested in an elimination diet approach to disease management
Treatment: Assay directed diet change
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Pilot Interventional Study of an EoE-Causal Food Identification Blood Test
- Fit questions
- Built from NCT07023380, who can take part
- Record updated
- 16 March 2026